二丹红藤败酱汤结合艾灸治疗慢性盆腔炎临床疗效观察_潘群玉.pdf

10 谷牧青,李扬璐,程姣姣,等.达英-35 对多囊卵巢综合征患者代谢与性激素的影响 J.首都医科大学学报.2019,40(04),560-565.11 苏椿淋,李昕,陆慧娟,等.达英-35 联合二甲双胍治疗多囊卵巢综合征合并子宫内膜不典型增生及早期子宫内膜样腺癌J.中华生殖与避孕杂志,2017,37(12):975-979.12 杨志平,吴昕.达英-35 联合二甲双胍治疗 38 例多囊卵巢综合征 J.中国实验方剂学杂志,2011,17(11):246-248.13 周艳,李莉莉,刘子铃.联合用药对 PCOS 伴不孕患者血 LH水平及受孕率的作用分析 J.河北医药,2018,40(15):2323-2326.14Chung JP,Yiu AK,CHung TK,et al.Arandomized crlssoverstudy of medroxyprogesterone acetate and Diane-35 in adolescentgirls with polycystic ovarian syndrome J.J Pediatr Adolesc Gyne-col,2014,27(3):166-171.15 韦丛丽.中药复方联合达英-35 对多囊卵巢综合征患者性激素水平的影响 J.中国实验方剂学杂志,2011,17(5):238-240.16 陈蓓蓓,张晓沁.张仲景体质学说在多囊卵巢综合征诊治中的应用 J.四川中医,2020,38(3),42-44.17 曾蕾,林欣仪,曾芳冬,等.罗颂平治疗肾虚痰湿型多囊卵巢综合征中药周期序贯疗法规律探讨 J.时珍国医国药,2021,31(5),1247-1250.18 冯晓,许朝霞,冯路,等.肝郁型多囊卵巢综合征的中医证治研究进展 J.世界科学技术-中医药现代化,2020,22(9),3338-3342.19 Mehta R,Kaur M,Gandhi P,et al.Auditory and visual reactiontime in polycystic ovarian syndrome J.J Clin Diagn Res,2018,12(6):CC11-CC13.20 黄一鸣,康开彪,潘文,等.基于数据挖掘多囊卵巢综合征的中医辨证用药规律分析 J.新中医,2018,50(6):60.21 宋根伟,张晓燕,姚霜.补肾中药的药理作用研究概况 J.山西医药杂志.2011,40(08):787-789.22 苗明三,彭孟凡,闫晓丽,等.菟丝子总黄酮对多囊卵巢综合征大鼠模型的影响 J.中国实验方剂学杂志,2019,25(5),143-150.(收稿日期 2021-06-07)基金项目:海南省卫生计生行业科研项目(编号:15A200091)二丹红藤败酱汤结合艾灸治疗慢性盆腔炎临床疗效观察潘群玉,许浪萍,莫政(三亚市中医院妇产科,海南 三亚 572000)摘要:目的:探究二丹红藤败酱汤结合艾灸治疗慢性盆腔炎临床效果。方法:研究纳入慢性盆腔炎患者 105 例(2020 年 3 月2021 年 6 月收治),并以随机数字表法将 105 例患者随机分为两组,对照组和观察组,分别 52 例、53例,对照组予头孢曲松钠与甲硝唑结合治疗,观察组予头孢曲松钠与甲硝唑结合治疗+二丹红藤败酱汤结合艾灸治疗,比较各组患者治疗效果、治疗前后局部体征(子宫、附件、宫骶韧带)评分变化、中医症状积分(下腹刺痛或胀痛、带下量多、脘腹胀满、经前乳房胀痛、情志抑郁、烦躁等)变化、血清白介素-2(IL-2)、白介素-8(IL-8)及肿瘤坏死因子 (TNB-)水平变化、不良反应。结果:与对照组(82.69%)比较,观察组(96.23%)有效率更高(P0.05),治疗后两组患者局部体征(子宫、附件、宫骶韧带)评分、中医证候积分(下腹刺痛或胀痛、带下量多、脘腹胀满、经前乳房胀痛、情志抑郁、烦躁等)及 IL-2、IL-8、TNB-等指标均改善,且观察组优于对照组(P0.05);对照组1 例恶心,观察组 1 例头晕,不良反应发生例数均较少。结论:慢性盆腔炎患者采取二丹红藤败酱汤与艾灸治疗结合临床效果良好,安全可行,值得应用。关键词:慢性盆腔炎;二丹红藤败酱汤;艾灸;疗效 中图分类号:R 711.33 文献标志码:A 文章编号:1000-3649(2023)02-0173-04 Clinical Effective Observation of Using Erdan Hongteng Baijiang Decoction Combined with Mmoxibustion in theTreatment of Chronic Pelvic Inflammatory Disease/PAN Qunyu,XU Langping,MO Zheng/Department of Gynaecology,Sanya Municipal Hospital of Traditional Chinese Medicine(Sanya Hainan 572000,China)Abstract:Objective:To explore the clinical effect of using Erdan Hongteng Baijiang Decoction combined with moxibustionin treating chronic pelvic inflammatory disease.Methods:This study included 105 patients with chronic pelvic inflammatory dis-ease(admitted from March 2020 to June 2021),and reduced 105 patients by the random number table method and randomly di-vided into two groups,a controlled group and an observation group,52 cases and 53 cases,respectively,were given Ceftriaxone3712023 年第 41 卷第 2 期Vol.41,No.2,2023四 川 中 医Journal of Sichuan of Traditional Chinese MedicineSodium and Mmetronidazole combined treatment of the controlled group.The observation group was treated with Ceftriaxone Sodi-um combined with Metronidazole and Erdan Hongteng Baijiang Decoction combined with moxibustion.Groups were compared be-fore and after the treatment effect,local signs(uterus,attachment,palace sacral ligaments)score changes,TCM syndrome inte-gral(ventral stabbing pain or tenderness,aginal discharge capacity was much,often abdominal distension full,premenstrualbreast tenderness,modern depression,irritability,etc.)change,serum interleukin-2(IL-2)and interleukin-8(IL-8)andtumor necrosis factor alpha(TNB-alpha)level changes,adverse reactions.Results:Compared with the controlled group(82.69%),the observation group(96.23%)had higher effective rate,P0.05.After treatment,the scores of local signs(uterus,adnexa,and uterosacral ligament),TCMsyndrome scores(lower abdomen tingling or distention pain,lower band quantity,abdominal distention,premenstrual breast dis-tention pain,depression,irritability,etc.),IL-2,IL-8,TNB-and other indicators were improved in each group.After treat-ment,the scores of local physical signs(uterus,adnexa,uterosacral ligament),TCM syndrome scores(lower abdomen tinglingor distention pain,more bands,depression or irritability,premenstrual breast distention,abdominal distention,etc.),IL-2,IL-8,TNB-and other indexes in the observation group were better than those in the controlled group,P0.05.There was 1case of nausea in the controlled group and 1 case of dizziness in the observation group.Conclusion:The combination of ErdanHongteng Baijiang Decoction and moxibustion therapy for chronic pelvic inflammatory disease patients has good clinical effect,safe and feasible,and is worthy of application.Keywords:Chronic pelvic inflammation;Erdan Hongteng Baijiang Decoction;Moxibustion;Curative effect慢性盆腔炎发生于女性患者生殖器及四周结缔组织、盆腔腹膜,表现为下腹疼痛、白带增多、腹胀等临床症状,若不采取有效方法治疗,将出现月经紊乱、盆腔痛、不孕等严重症状,对患者身心造成巨大影响1。临床治疗该病多采取抗菌、抗炎治疗,头孢曲松钠、甲硝唑等为常用药物,取得一定疗效2。为了提升慢性盆腔炎治疗效果,常采取中西医结合治疗该病,疗效显著,相关报道较多3-5。二丹红藤败酱汤、艾灸可较好改善慢性盆腔炎患者临床症状,治疗效果佳,值得深入探究。故而笔者纳入 105 例慢性盆腔炎患者分组研究二丹红藤败酱汤结合艾灸治疗效果及临床价值,报道如下。1资料与方法1.1一般资料研究纳入慢性盆腔炎患者 105 例(2020 年 3 月2021 年 6 月收治),并以随机数字表法将 105 例患者分成两组,对照组和观察组,分别52 例、53 例。对照组:52 例,年龄 24 岁 42 岁,平均年龄(31.242.12)岁;病程 3 19 个月,平均病程(11.252.36)个月;轻度 22 例,中度 21例,重度 9 例。观