21论著影像研究与医学应用2024年1月第8卷第1期结扎不同左冠状动脉分支对大鼠左室结构和功能的影响崔岩芳，万伟平，黄春燕，韩超（通信作者）（烟台山医院超声科山东烟台264003）EffectsofligationofdifferentbranchesofLeftcoronaryarteryonleftventricularstructureandfunctioninratsCUIYanfang,WANWeiping,HUANGChunyan,HANChao(Correspondingauthor)DepartmentofUltrasound,YantaishanHospital,Yantai,Shandong264003,China【Abstract】ObjectiveBasedonthedifferencesofcoronaryarteryanatomybetweenratandhuman,echocardiographywasusedtoinvestigatetheeffectsofligationofleftanteriordescendingarteryandleftcircumflexarteryonleftventricularstructureandejectionfraction.Methods24Wistarratswererandomlydividedintoleftanteriordescendingartery(LAD)groupandleftcircumflexartery(LCX)groupaccordingtoage.Leftatrialdiameter,leftventriculardiameterandvolume,leftventricularejectionfractionandsoonwereobservedbyechocardiography.ResultsComparedwiththetwogroups,theheartrate,leftatrialdiameterandleftventricularend-diastolicdiameterincreasedaftersurgery(P<0.05),andleftventricularejectionfractiondecreased(P<0.05),withstatisticaldifferences,buttherewasnosignificantdifferenceinaorticdiameterbeforeandaftersurgery(P>0.05).Furtheranalysisshowedthattheleftatrialdiameterandleftventricularend-diastolicdiameterincreasedandleftventricularejectionfractiondecreasedinLCXgroupafteroperationcomparedwiththatbeforeoperation(P<0.05),buttherewasnostatisticaldifferenceintheformercomparedwithLADgroup(P<0.05).ConclusionLigationofthecircumflexbranchcanalsoenlargetheleftatrioventricularandaffecttheleftventricularejectionfunction,butthelatterhaslesseffectthanthedescendingbranchbeforeligation.【Keywords】Heart;Acuteischemicmodel;Echocardiography;Rats【摘要】目的：基于大鼠与人体冠状动脉解剖结构的差异，通过超声心动图探讨结扎大鼠前降支与回旋支对左室结构及射血分数的影响。方法：24例Wistar大鼠按月龄配伍后随机分为前降支（LAD）组和回旋支（LCX）组，超声心动图观察各组左房内径、左室内径及容积、左室射血分数等。结果：两组术后与术前相比，心率、左房内径、左室舒张末...
