·626·疑难病杂志2024年5月第23卷第5期ChinJDifficandComplCas,May2024,Vol.23,No.5[D01】10.3969/j.issn.1671-6450.2024.05.024结缔组织病相关肺间质病进展倾向的监察研究现状综述鲁萍萍，李嘉祺综述刁鑫审校基金项目：陕西省科技厅社会发展项目（2022SF-554）作者单位：710077西安医学院第一附属医院呼吸与危重症医学科通信作者：刁鑫,E-mail:yuheng_922@163.com【摘要】结缔组织病(（CTD)是一组累及全身结缔组织的自身免疫疾病。间质性肺病(ILD）是CTD常见的肺部并发症。结缔组织病相关肺间质病的预后不一,部分患者通过治疗,ILD的影像学改变逆转；部分患者ILD病变无法逆转，但可长期维持稳定；还有部分患者虽经积极治疗,ILD仍持续进展，最终发展为呼吸衰竭。因此全面了解结缔组织病相关肺间质病(CTD-ILD)的进展倾向对于制定个体治疗方案及改善患者的预后具有重大的意义。文章就关于结缔组织病相关肺间质病进展倾向的研究现状进行综述。【关键词】结缔组织病相关肺间质病；严重程度；预后因素【中图分类号】R593.2;R563.9StatusofmonitoringthetendencyofconnectivetissuediseaserelatedinterstitiallungdiseaseLuPingping,LiJiaqi,DiaoXin.DepartmentofRespiratoryandCriticalCare,TheFirstAffiliatedHospitalofXi'anMedicalCollege,ShaanxiProvince,Xian710077,ChinaFundingprogram:SocialDevelopmentProjectofShaanxiScienceandTechnologyDepartment(2022SF-554)Correspondingauthor:DiaoXin,E-mail:yuheng_922@163.com[Abstract]Connectivetissuedisease(CTD)isagroupofautoimmunediseasesthatinvolveconnectivetissuethroughoutthebody.Interstitiallungdisease(ILD)isacommoncomplicationofCTD.Theprognosisofconnectivetissuediseaserelatedinterstitiallungdisease(CTD-ILD)isvariable,imagingchangesofCTD-ILDcanbereversedinsomepatientsaftertreatment,ILDlesionsinsomepatientscouldnotbereversed,butcouldremainstableforalongtime;insomepatients,despiteactivetreatment,ILDcontinuestoprogressandeventuallydevelopsrespiratoryfailure.Therefore,acomprehensiveunderstandingoftheprogressiontendencyofconnectivetissuediseaserelatedinterstitiallungdiseaseisofgreatsignifi-cancefordevelopingindividualtreatmentplansandimprovingtheprognosisofpatients.Thisarticlereviewsthecurrentsta-tusofresearchontheprogression...
