13论著影像研究与医学应用2024年3月第8卷第6期系统性红斑狼疮患者骨密度与部分免疫指标的相关性研究陈显杰1，黄婉敏2，李耀国1，莊高明1（1广州市番禺区中心医院影像科广东广州511400）（2广州市番禺区中心医院肿瘤科广东广州511400）CorrelationbetweenbonemineraldensityandsomeimmuneindexesamongpatientswithsystemiclupuserythematosusCHENXianjie1,HUANGWanmin2,LIYaoguo1,ZHUANGGaoming11DepartmentofImaging,PanyuCentralHospital,Guangzhou,Guangdong511400,China;2DepartmentofOncology,PanyuCentralHospital,Guangzhou,Guangdong511400,China【Abstract】ObjectiveToinvestigatethecorrelationbetweenbonemineraldensity(BMD)andsomeimmuneindexesinpatientswithsystemiclupuserythematosus(SLE),andwhetherimmuneindexesaffectBMDinpatientswithSLE.MethodsUsingaretrospectivestudymethod,43adultpatientsadmittedtothePanyuCentralHospital,GuangzhoufromJanuarytoMay2023duetoSLEdiseasewereselectedasthestudysubjects.Lumbarvertebrabonedensitywasdetectedbydual-energybonedensitometer,duringwhichimmuneindexessuchasESR,complementC3,complementC4,IgA,IgG,IgMandCRPweremonitored,andbasicpersonaldatasuchasage,sex,weightandheightwererecorded.ResultsTheaverageageof43SLEpatientswas(51.12±14.13)yearsold.67.44%ofpatientshadabnormalbonemetabolism,51.16%haddecreasedbonemass,and16.28%hadosteoporosis.ThelinearrelationshipbetweentheobservedindicatorswasanalyzedbyPearsonmethod.MultipleregressionanalysisshowedthatcomplementC3,IgMandagewerethemaininfluencingfactorsofBMD.ConclusionThedecreaseofimmuneindexconcentrationwillleadtothechangeofbonemineraldensityinpatientswithsystemiclupuserythematosus,andtheincreaseofageandthedecreaseofIgMandC3indexconcentrationwillleadtothesignificantdecreaseofbonemineraldensityinpatientswithSLE.【Keywords】Systemiclupuserythematosus;Bonemineraldensity;ComplementC3;IgM【摘要】目的：探讨系统性红斑狼疮（SLE）患者骨密度（BMD）与部分免疫指标的相关性及免疫指标是否影响SLE患者BMD。方法：采用回顾性研究方法，选取2023年1月—5月在广州市番禺区中心医院因患SLE住院的成年患者43例为研究对象。采用双能骨密度仪检测患者腰椎骨密度，期间...
