胶原蛋白海绵在腰椎间盘突出症手术后的止血作用研究唐尚权1徐新华摘要：目的：探讨胶原蛋白海绵在腰椎间盘突出症手术中的止血作用。方法：选择在本院脊柱外科收治的椎间盘突出症单纯行半椎板减压髓核摘除的患者，随机分为两组，一组用胶原蛋白海绵覆盖在硬脊膜外后缝合切口，另一组不用胶原蛋白海绵，直接缝合切口，记录患者术后24、48h内引流血量，根据手术前、后血红蛋白检测结果计算患者血红蛋白的丢失量，并对两组数据进行比较。结果:应用胶原蛋白海绵组引流量较不用组引流量少，二者间具有显著性差异。结论：在腰椎半椎板减压髓核摘除术后应用胶原蛋白海绵可以明显减少椎管内出血，临床值得推荐。关键词：胶原蛋白海绵；腰椎间盘突出症；止血Thehemostaticeffectofcollagenspongeinthesurgicaltreatmentoflumbardischerniation/TANGshang-quan，XUxin-hua.DepartmentofOrthopaedics,AfficationMindaHospitalofHuBeiInstitutefornationality,Enshi,Hubei,China，445000,[Abstract]Objective:Tostudythehemostaticeffectofcollagenspongeinthesurgicaltreatmentoflumbardischerniation.Methods:76patientswererandomlydividedintotwogroups,Agroup(34cases)wereusedcollagenspongeinoperationandBgroup(42cases)werenotusedcollagensponge.Thedrainagevolumesat24and48hoursafteroperationwererecordedandlossofhemoglobinwascalculatedaccordingtothehemoglobincountsbeforeandafteroperation．AllthedatawerestatisticallyanalyzedusingSPSS13．0software．Results:Thereweresignificantdifferencesbetweenthe2groupsindrainagevolumesat24and48hoursafteroperation,hemoglobinlossat48hoursafteroperation(P<0．05)．Conclusions:Thereismorehemostaticeffecttousingcollagenspongeinthesurgicaltreatmentoflumbardischerniation.[Keywords]Collagensponge；Hemostasis;Lumbardischerniation腰椎间盘突出症（LumbarDiscHerniation,LDH）是脊柱外科的常见病、多发病。通过摘除突出的髓核组织来消除其对神经根的压迫成为治疗腰椎间盘突出症行之有效的手术方法。但手术也有创伤，手术后出血是其中较常见的并发症之一，笔者在观察胶原蛋白海绵的防神经根粘连作用时，发现其术后引流要少，从而对其止血作用进行了前瞻性对比观察，报道如下：1对象和方法1作者单位：湖北民族学院附属民大医院骨外1科，湖北恩施，445000作者简介：唐尚权，男，39岁，...
