ChinJProsthodont,September2023,Vol.24,No.5口腔颌面修复学杂志2023年9月第24卷第5期骨质疏松状态下不同种植体表面涂层改性技术对种植体骨结合的影响骨质疏松状态下不同种植体表面涂层改性技术对种植体骨结合的影响*张婷婷李潇刘莉【摘要】钛及钛合金种植体广泛应用于牙列缺损和缺失的修复。骨质疏松患者由于种植体骨结合不良和初期稳定性不佳，存在较高的失败风险。因此，探究骨质疏松状态下如何促进种植体骨结合具有重要的临床意义。近年来关于骨质疏松状态下不同种植体表面涂层改性的研究主要可分为无机材料、生物分子、金属材料、中药类涂层以及具有治疗效果的药物涂层五大类。各类涂层改性的作用机制和生物学效果不尽相同，本文将对骨质疏松状态下不同种植体表面涂层改性技术对种植体骨结合的影响进行分析综述。关键词：种植体；表面涂层；骨质疏松；骨结合［中国图书分类号］R783.1［文献标识码］ADOI:10.19748/j.cn.kqxf.1009-3761.2023.5.014EffectofdifferentsurfacecoatingmodificationtechniquesonosseointegrationofimplantinosteoporosisZHANGTing-ting1,LIXiao2*,LIULi3.(1.SchoolofStomatology,SouthernMedicalUniversity,Guangzhou510515,China;2.DepartmentofStomatology,GeneralHospitalofSouthernTheaterCommand,PLA,Guangzhou510010,China;3.SchoolofStomatology,JinanUniversity,Guangzhou510000,China)【Abstract】Titaniumandtitaniumalloyimplantshavebeenwidelyusedintherepairofdentitiondefectsanddentitionloss,buttheyhaveahighriskoffailureforpatientswithosteoporosisbecauseoftheunsatisfactoryosseointegrationandprimaryimplantstability.Therefore,ithasgreatclinicalsignificancetoexplorehowtopromoteimplantosseointegrationinosteoporoticstate.Inrecentyears,theresearchonthemodificationofdifferentimplantsurfacecoatingsundertheosteoporosisconditioncanbedividedintofivecategories:inorganicmaterials,biomolecules,metalmaterials,traditionalChinesemedicinecoatingsanddrugcoatingswiththerapeuticeffects.Themechanismsandbiologicaleffectsofvariouscoatingmodificationsaredifferent.Thisarticlewillanalyzeandreviewtheeffectsofdifferentimplantsurfacecoatingsmodificationtechniquesonosseointegrationinosteoporosis.Keywords:implant;surfacecoating;osteoporosis;osseointegration...
