Pyroptosis, metabolism, and tumor immune microenvironment.pdfVIP免费

Received:31January2021Revised:17June2021Accepted:21June2021Publishedonline:29July2021DOI:10.1002/ctm2.492REVIEWPyroptosis,metabolism,andtumorimmunemicroenvironmentTiantianDu1,#JieGao1,#PeilongLi1,#YunshanWang1QiuchenQi1XiaoyanLiu1JuanLi1ChuanxinWang1,2,3LutaoDu1,2,31DepartmentofClinicalLaboratory,TheSecondHospital,CheelooCollegeofMedicine,ShandongUniversity,Jinan,Shandong,China2ShandongEngineeringandTechnologyResearchCenterforTumorMarkerDetection,Jinan,Shandong,China3ShandongProvincialClinicalMedicineResearchCenterforClinicalLaboratory,Jinan,Shandong,ChinaCorrespondenceLutaoDu,ChuanxinWang,andJuanLi,DepartmentofClinicalLaboratory,TheSecondHospital,CheelooCollegeofMedicine,ShandongUniversity,247BeiyuanStreet,Jinan250033,Shandong,China.Email:lutaodu@sdu.edu.cn;cxwang@sdu.edu.cn;niderouke@163.comGraphicalAbstract1.Gasderminsareexecutorsofpyroptosis,whichcauseinflammatorycelldeath,accompaniedwithvariousinflammatorymediators.2.Pyroptosisplaysadualroleintumormicroenvironment,includinganti-tumorandpro-tumoreffects.3.Pyroptosiscanbeusedasanewtargettofightagainstthetumor.Clin.Transl.Med.2021;11:e492.wileyonlinelibrary.com/journal/ctm2https://doi.org/10.1002/ctm2.492Received:31January2021Revised:17June2021Accepted:21June2021Publishedonline:29July2021DOI:10.1002/ctm2.492REVIEWPyroptosis,metabolism,andtumorimmunemicroenvironmentTiantianDu1,#JieGao1,#PeilongLi1,#YunshanWang1QiuchenQi1XiaoyanLiu1JuanLi1ChuanxinWang1,2,3LutaoDu1,2,31DepartmentofClinicalLaboratory,TheSecondHospital,CheelooCollegeofMedicine,ShandongUniversity,Jinan,Shandong,China2ShandongEngineeringandTechnologyResearchCenterforTumorMarkerDetection,Jinan,Shandong,China3ShandongProvincialClinicalMedicineResearchCenterforClinicalLaboratory,Jinan,Shandong,ChinaCorrespondenceLutaoDu,ChuanxinWang,andJuanLi,DepartmentofClinicalLaboratory,TheSecondHospital,CheelooCollegeofMedicine,ShandongUniversity,247BeiyuanStreet,Jinan250033,Shandong,China.Email:lutaodu@sdu.edu.cn;cxwang@sdu.edu.cn;niderouke@163.comAbstractInresponse...