Neuronal and Glial Cell Markers Interactive Diagram.pdf

Cell Signaling Technology 20032018 Cell Signaling Technology,INeuronal and Glial Cell Marker AtlasPathway Diagram KeyDirect Stimulatory Modification Direct Inhibitory ModificationMultistep Stimulatory Modification Multistep Inhibitory ModificationTentative Stimulatory Modification Tentative Inhibitory ModificationTranscriptional Inhibitory ModificationPathway Diagram KeyOligodendrocytesNeuroepithelial Cells*Neural Stem Cell Markers-Musashi-Notch1-SSEA1-E-Cadherin-HES1-NestinProliferating Cell Markers:-BrdU-Ki-67-PCNASchwann CellsGlutamatergicNeuronsAlzheimers DiseaseParkinsons DiseaseALSGABAergicNeuronsDopaminergicNeuronsSerotonergicNeuronsCholinergicNeuronsInterneuronsMotor NeuronsAstrocytesMature NeuronsIntermediate Progenitors*-EAAT1(GLAST-1)-EAAT2(GLT-1)-GAP43-GFAP-A2B5-CNPase-MAG-MOG-A2B5-ALDH1L1-EAAT1(GLAST-1)-EAAT2(GLT-1)-GFAP-Notch-S100B-EOMES(Tbr2)-Neurogenin 2-Pax6Cell Type MarkersNeurodegenerative Disease-Associated MarkersImmature NeuronsNeurotransmittersNeuronal Subtypes-Doublecortin-NeuroD1-TBR1-3-Tubulin-Myelin Basic Protein-NCAM-p75NTR-S100BRadial Glia*Microglia-BLP(FABP7)-N-Cadherin-GFAP-EAAT1(GLAST-1)-ASC-CD11b(ITGAM)-CD40-CD45-CD68Homeostatic:-C1qA/B-CX3CR1-Cystatin 3 (CST3)-P2RY12Stage 1Upregulated-ApoE-DAP12 (TYROBP)-TREM2Functional Markers:-Arg3.1(Arc)-CaMKII-CREB-EGR1-Erk-c-Fos-PKA*Proliferating Cells Stage 2(TREM2-Dependant)-Axl-Cystatin F (CST7)-Nestin-Sox2-Tenascin C-Vimentin-Myelin Basic Protein-NG2-Olig2-SOX10-VGLUT1/2-ChAT-Calbindin-Calretinin-5-HT3A Receptor-ChAT-HB9-Islet-1/2-ADORA2A-DARPP-32-GAD1/2-Amyloid(A)-ApoE-CD33-Presenilin 1/2(PSEN1/2)-Tau-TREM2-DJ-1-GBA-LRRK2-Parkin-PINK1-Synuclein-UCHL1-VPS35-C9orf72-FUS-SOD1-SQSTM1-TDP43-Neuropeptide Y-Penk-ALDH1A1-FoxA2-GIRK2-FEV-SERT-TPH2-Tryptophan Hydroxylase-Lmx1B-Tyrosine Hydroxylase-MAP2-NeuN-Neurofilament-H-Neurofilament-L-Neurofilament-M-Parvalbumin-Somatostatin-VIP-Neurogenin 2-Olig2-Notch1-Sox2-Sox10-Neuron Specific Enolase(NSE)-Tau-Thy1-3-Tubulin-UCHL1Downregulated-P2RY12-CX3CR1-TMEM119-CD33-Dectin-1 (CLEC7a)-CD11c(ITGAX)-Spp1-F4/80-Iba1-PU.1-TMEM119Disease-Associated Microglia(DAM)rev.06/18