第51卷第9期2023年5月广州化工GuangzhouChemicalIndustryVol.51No.9May.2023火焰原子吸收分光光度法测定化妆品中总镉的含量的测量不确定度评定程如雾,石兴红,杨淡梅,刘兆宾,符秋美,邱颖姮,邬晓鸥(深圳市药品检验研究院,国家药品监督管理局化妆品监测评价重点实验室,广东深圳518057)摘要:采用微波消解法处理样品、火焰原子吸收分光光度法测定化妆品中总镉的含量,并根据《JJF1059.1-2012测量不确定度评定与表示》建立数学模型,对上述方法的不确定度进行分析评定。经计算,其测量不确定度主要来源于标准曲线拟合及测量重复性,而称样及稀释过程引入的不确定度则较小;因此,为降低不确定度,提高结果准确性,需定期对仪器进行检定,以保证仪器处于稳定良好的状态。关键词:火焰原子吸收分光光度法;化妆品;总镉;不确定度中图分类号:TQ658.2文献标志码:A文章编号:1001-9677(2023)09-0088-04第一作者:程如雾(1994-),女,药师,主要从事保健食品、化妆品检测。通讯作者:石兴红(1986-),女,主管药师,主要从事药品、保健食品、化妆品检验。EvaluationofMeasurementUncertaintyinDeterminationofTotalCadmiuminCosmeticsbyFlameAtomicAbsorptionSpectrophotometryCHENGRu-wu,SHIXing-hong,YANGDan-mei,LIUZhao-bin,FUQiu-mei,QIUYing-heng,WUXiao-ou(NMPAKeyLaboratoryforMonitoringandEvaluationofCosmetics,ShenzhenInstituteforDrugControl,GuangdongShenzhen518057,China)Abstract:Thesamplesweretreatedbymicrowavedigestionandthecontentoftotalcadmiumincosmeticswasdeterminedbyflameatomicabsorptionspectrophotometry.AmathematicalmodelwasestablishedaccordingtoJJF1059.1-2012EvaluationandExpressionofUncertaintyinMeasurement,theuncertaintyoftheabovemethodswasanalyzedandevaluated.Theuncertaintyofmeasurementwasmainlyderivedfromthefittingandmeasurementrepeatabilityofstandardcurve,whiletheuncertaintyintroducedintheweighingsampleanddilutionprocesswassmaller.Therefore,inordertoreducetheuncertaintyandimprovetheaccuracyoftheresults,theinstrumentshouldbeconfirmedregularlytoensuretheinstrumentwasinastableandgoodstate.Keywords:flameatomicabsorptionspectrophotometry;cosmetics;totalcadmium;measurementuncertainty化妆品是指以涂擦、喷洒或者其他类似的方法散布于人体表面任何部位(皮肤、毛发、指甲、口唇等),以达到清洁...
