oryTractInfectionEffectofMechanicalVent(临床工程）·论著·1049.临床医学工程星2023年8月第30卷第8期机械通气联合头孢哌酮舒巴坦治疗呼吸道感染合并呼吸衰竭的效果凌耿飞1，曹聪聪²，韩世杰1（周口市中心医院呼吸与危重症医学科，河南周口466000；2周口职业技术学院基础医学教研室，河南周口466000)【摘要】目的探讨机械通气联合头孢哌酮舒巴坦治疗呼吸道感染合并呼吸衰竭的效果。方法100例呼吸道感染合并呼吸衰竭患者随机分为两组，对照组采用机械通气+头孢唑治疗，观察组采用机械通气+头孢哌酮舒巴坦治疗，比较两组的治疗效果。结果观察组的总有效率高于对照组，退热、症状改善、血气分析指标好转及住院时间均短于对照组，治疗后IL-6、CRP、PCT水平低于对照组（P<0.05）。结论机械通气联合头孢哌酮舒巴坦治疗呼吸道感染合并呼吸衰竭效果显著，可抑制炎性介质表达【关键词】机械通气；头孢哌酮舒巴坦；呼吸道感染；呼吸衰竭中图分类号：R56文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.08.1049ithCefoperazoneSulbactamintheTreatmentofRespiratilationCombinedwithCefoperazoneSulbactamintheTrComplicatedwithRespiratoryFailure//LINGGengfei',CAOCongcong',HANShijie(DepartmentofRespiratoryandCriticalCareMedicine,ZhoukouCentralHospital,Zhoukou466000,China,?BasicMedicalTeachingandResearchSection,ZhoukouVocationalandTechnicalCollege,Zhoukou466000,China)[Abstract]ObjectiveToexploretheeffectofmechanicalventilationcombinedwithcefoperazonesulbactaminthetreatmentofrespiratorytractinfectioncomplicatedwithrespiratoryfailure.Methods1oopatientswithrespiratorytractinfectioncomplicatedwithrespiratoryfailurewererandomlydividedintotwogroups.Thecontrolgroupwastreatedwithmechanicalventilation+ceftizoxime,andtheobservationgroupwastreatedwithmechanicalventilation+cefoperazonesulbactam.Thetherapeuticeffectsofthetwogroupswerecompared.ResultsThetotaleffectiverateoftheobservationgroupwashigherthanthatofthecontrolgroup,theantipyretictime,symptomimprovementtime,bloodgasanalysisindeximprovementtimeandhospitalizationtimewereshorterthanthoseofthecontrolgroup,andthelevelsofIL-6,CRPandPCTaftertreatmentwerelowerthanthoseofthecontrolgroup(P<0.05).ConclusionsMechanicalvent...
