2023年2月第30卷第2期阿奇霉素联合头孢哌酮舒巴坦治疗大叶性肺炎患儿的效果分析李满喜1，宋小军2（1漯河市中医院儿科，河南漯河462000；2漯河市第二人民医院急诊科，河南漯河462000）【摘要】目的分析阿奇霉素联合头孢哌酮舒巴坦治疗大叶性肺炎患儿的效果。方法80例大叶性肺炎患儿随机分为常规组（头孢哌酮舒巴坦）和联合组（阿奇霉素联合头孢哌酮舒巴坦），比较两组的临床疗效、临床症状改善情况、呼吸力学参数及不良反应。结果治疗后，联合组的总有效率明显高于常规组，退热时间、啰音消失时间和咳嗽消失时间均明显短于常规组（P＜0.05）。治疗后，联合组的胸廓顺应性、肺顺应性、总动态顺应性均明显高于常规组（P＜0.05）。结论阿奇霉素联合头孢哌酮舒巴坦治疗大叶性肺炎患儿的效果显著，可有效改善患儿的临床症状，提高呼吸力学参数，安全性较高。【关键词】阿奇霉素；头孢哌酮舒巴坦；大叶性肺炎；临床疗效中图分类号：R725.6文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.02.0191AnalysisontheEffectofAzithromycinCombinedwithCefoperazoneSulbactamintheTreatmentofChildrenwithLobarPneumonia//LIManxi1,SONGXiaojun2(1DepartmentofPediatrics,LuoheHospitalofTraditionalChineseMedicine,Luohe462000,China;2DepartmentofEmergency,LuoheSecondPeople'sHospital,Luohe462000,China)[Abstract]ObjectiveToanalyzetheeffectofazithromycincombinedwithcefoperazonesulbactaminthetreatmentofchildrenwithlobarpneumonia.Methods80casesofchildrenwithlobarpneumoniawererandomlydividedintotheconventionalgroup(cefoperazonesulbactam)andthecombinedgroup(azithromycincombinedwithcefoperazonesulbactam).Theclinicalefficacy,improvementofclinicalsymptoms,respiratorymechanicsparametersandadversereactionswerecomparedbetweenthetwogroups.ResultsAftertreatment,thetotaleffectiverateofthecombinedgroupwassignificantlyhigherthanthatoftheconventionalgroup,andthedisappearancetimeoffever,raleandcoughweresignificantlyshorterthanthoseoftheconventionalgroup(P<0.05).Aftertreatment,thehoraciccompliance,lungcomplianceandtotaldynamiccomplianceofthecombinedgroupweresignificantlyhigherthanthoseoftheconventionalgroup(P<0.05).ConclusionsAzithromycincombinedwithcefoperazonesulbactaminthetreatmentofchil...
