【DOI】10.3969/j.issn.1671 ̄6450.2023.08.021综述肠道菌群与胆固醇结石、胆色素结石形成关系的研究进展樊凤良综述孙海军审校作者单位:150000哈尔滨医科大学附属第一医院普外科通信作者:孙海军ꎬE ̄mail:15945777708@163.com【摘要】胆囊结石作为消化系统中的常见病ꎬ近些年发病率不断增加ꎮ目前对胆囊结石的具体机制尚不清楚ꎬ正常胆囊一般认为不存在细菌ꎬ而肠道菌群也有自己的稳态ꎬ研究表明肠道菌群失衡在胆囊结石形成过程中发挥重要作用ꎮ文章对胆固醇结石和胆色素结石形成与肠道菌群的关系作一综述ꎮ【关键词】胆囊结石ꎬ胆色素ꎻ胆囊结石ꎻ胆固醇ꎻ肠道菌群ꎻ胆汁酸循环【中图分类号】R575.6+2【文献标识码】AResearchprogressontherelationshipbetweenGutmicrobiotaandtheformationofcholesterolgallstonesandpigmentgallstonesFanFengliangꎬSunHaijun.DepartmentofGeneralSurgeryꎬTheFirstAffiliatedHospitalofHarbinMedicalUni ̄versityꎬHeilongjiangProvinceꎬHarbin150000ꎬChinaCorrespondingauthor:SunHaijunꎬE ̄mail:15945777708@163.com【Abstract】Asacommondiseaseinthedigestivesystem,theincidenceofcholecystolithiasishasbeenincreasinginrecentyears.Atpresent,thespecificmechanismofcholecystolithiasisisnotclear.Normalgallbladderisgenerallybelievedtobefreeofbacteria,andGutmicrobiotaalsohasitsownsteadystate.ResearchshowsthattheimbalanceofGutmicrobio ̄taplaysanimportantroleintheformationofcholecystolithiasis.ThisarticlereviewstherelationshipbetweentheformationofcholesterolgallstonesandpigmentgallstonesandGutmicrobiota.【Keywords】Gallstonesꎬbiliarypigment;Gallstones,cholesterol;Intestinalflora;Bileacidcycle胆囊结石(cholecystolithiasis)作为人类消化系统最常见的疾病之一ꎬ随着人们近些年来生活水平的提高ꎬ发病率也在逐年攀升ꎮ胆囊结石主要包...