现代泌尿外科杂志·临床研究·伴发结石的原发性上尿路尿路上皮癌患者延迟诊断7例分析金滨，吕政通,王森,吴鹏杰,马宏，陈鑫,刘明（1.北京医院泌尿外科；2.国家老年医学中心；3.中国医学科学院老年医学研究院，北京100730）Analysisof7casesofdelayeddiagnosisofprimaryuppertracturothelialcarcinomawithcalculiJINBin,LYUZhengtong,WANGMiao,WUPengjie,MAHong,CHENXin,LIUMing(1.DepartmentofUrology,BeijingHospital;2.NationalCenterofGerontology;3.InstituteofGeriatricMedicine,ChineseAcademyofMedicalSciences,Beijing100730,China)ABSTRACT:ObjectiveToreducethemisdiagnosisratebyanalyzingtheclinicaldataofpatientswithprimaryuppertracturothelialcarcinoma(UTUC)complicatedwithcalculi.MethodsClinicaldataof7UTUCwithcalculipatientstreatedduringSep.2018andApr.2022wereretrospectivelyanalyzed,includinggeneraldata,timefromvisittodiagnosis,imagingdata,urineexudationcytologicalresults,surgicalmethods,pathologicalstagesandfollow-updata.ResultsTheratioofmaletofemalewas3:4,andthemeanagewas66.4(55-72)years.Theinitiateimagingexaminationresultsonlyshowedcalculi,butdidnotindicatesuspicioustumor(including1casewithmissingdata).Themediantimefromthefirstvisittodiagnosiswas12months(5-36months).Ofall7cases,2（2/4)wereclinicallydiagnosedbyenhancedCT,3（3/4)byMRI,and2（2/7)bypositiveurineexudationcytology.Allpatientsreceivedsurgicaltreatment.Postoperativepathologyshowed85.71%(6/7)werehigh-gradeUTUC.PostoperativestagingwasTINOMOin4cases,T3NOMOin2cases,andT4N2MOin1case.Adjuvantchemotherapywasconductedin2cases.Duringthemedianfollow-upof12months(6-41),lcasedevelopedmultiplesystemicmetastasesinmonth9,whiletheothercaseshadnorecurrenceormetastasis.ConclusionForUTUCpatientswithoutobviousfillingdefectonimaging,especiallywhenipsilateralcalculiwerecomplicated,misdiagnosisshouldbealertedfortimelytreatmentandbetterprognosis.KEYWORDS:uppertracturothelialcarcinoma;urinarycalculi;carcinomaoftheureter;carcinomaofrenalpelvis摘要：目的分析伴结石的原发性上尿路尿路上皮癌患者(UTUC)的临床资料，以降低此类患者的误诊率。方法回顾性分析在2018年9月一2022年...
