何勇,柴璐,祁兴顺,北部战区总医院消化内科辽宁省沈阳市110840何勇,柴璐,沈阳药科大学研究生院辽宁省沈阳市110016陈菡,北部战区总医院药剂科辽宁省沈阳市110840何勇,硕士,主要从事消化系统疾病方面的研究.作者贡献分布:本文由何勇查阅文献及撰写;柴璐、陈菡校正文章书写及格式;祁兴顺审校.通讯作者:祁兴顺,医学博士,主任,副主任医师,110840,中国辽宁省沈阳市文化路83号,北部战区总医院消化内科.xingshunqi@126.com收稿日期:2023-08-08修回日期:2023-08-30接受日期:2023-09-01在线出版日期:2023-09-08Effectofdifferentinfusionapproachesonsafetyandefficacyofterlipressin:CurrentcontroversiesYongHe,LuChai,HanChen,Xing-ShunQiYongHe,LuChai,Xing-ShunQi,DepartmentofGastroenter-ology,GeneralHospitalofNorthernTheaterCommand,Shenyang110840,LiaoningProvince,ChinaYongHe,LuChai,GraduateSchoolofShenyangPharmaceuticalUniversity,Shenyang110016,LiaoningProvince,ChinaHanChen,DepartmentofPharmacy,GeneralHospitalofNorthernTheaterCommand,Shenyang110840,LiaoningProvince,ChinaCorrespondingauthor:Xing-ShunQi,M.D.,Director,AssociateChiefPhysician,DepartmentofGastroenterology,GeneralofNorthernTheaterCommand,No.83WenhuaRoad,Shenyang110840,LiaoningProvince,China.xingshunqi@126.comReceived:2023-08-08Revised:2023-08-30Accepted:2023-09-01Publishedonline:2023-09-08AbstractTerlipressin,asyntheticanalogofvasopressin,hasbeenwidelyusedtotreatacutevaricealbleeding,hepatorenalsyndrome,andothercomplicationsofcirrhosis.However,amongdifferentinfusionapproachesofterlipressin,itssafetyandefficacyarealsoheterogeneous.Previousstudieshavedemonstratedthatcontinuousinfusionofterlipressinismoreeffectivewithalowerincidenceofadverseeventsthanintermittentintravenousinfusion.Thispaperaimstoreviewtherelevantliteratureandsummarizethedataregardingthesafetyandeffectivenessofdifferentinfusionapproachesofterlipressintoguideclinicalpractice.©TheAuthor(s)2023.PublishedbyBaishidengPublishingGroupInc.Allrightsreserved.KeyWords:Terlipressin;Intravenousinfusion;Cirrhosis;Acutevaricealbleeding;Hepatorenalsyndrome;Refractoryascites;SepticshockCitation:HeY,ChaiL,ChenH,QiX...