tationin(临床研究）·论著·.1083.临床医学工程2023年8月第30卷第8期丙泊酚复合瑞芬太尼靶控输注麻醉对腹腔镜结肠癌根治术患者镇静效果及躁动情况的影响刘奕君，谭秀娟，莫桂熙（广东医科大学附属医院麻醉手术中心，广东湛江524001）【摘要】目的探讨丙泊酚复合瑞芬太尼靶控输注麻醉对腹腔镜结肠癌根治术患者镇静效果及躁动情况的影响。方法120例行腹腔镜结肠癌根治术治疗的患者根据麻醉方法的不同分为两组，对照组采用丙泊酚复合舒芬太尼靶控输注麻醉，观察组采用丙泊酚复合瑞芬太尼靶控输注麻醉，比较两组的镇静效果、躁动情况及不良反应。结果观察组拔管后5min、拔管后10min以及拔管后30min的OAAS评分均高于对照组（P<0.05）。观察组苏醒时、苏醒后30min、苏醒后120min的Ramsay镇静评分均高于对照组，SAS评分均低于对照组（P<0.05)。观察组苏醒期间的不良反应总发生率为4.41%，低于对照组的21.15%（P<0.05)。结论丙泊酚复合瑞芬太尼靶控输注麻醉对腹腔镜结肠癌根治术患者的镇静效果较好，可明显减轻患者躁动情况，且安全性较高。【关键词】丙泊酚；瑞芬太尼；靶控输注；腹腔镜结肠癌根治术；镇静；躁动情况中图分类号：R614文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.08.1083ImpactofPropofolCombinedwithRemifentanilTarget-ControlledInfusionAnesthesiaonSedationEffectandAgPatientsUndergoingLaparoscopicRadicalResectionofColonCancerIILIUYijun,TANXiujuan,MOGuixi(AnesthesiaSurgeryCenter,theAffiliatedHospitalofGuangdongMedicalUniversity,Zhanjiang524001,China)(AnesthesiaSurgeryCenter,theAffiliatedHospitalofGuangdongMedicalUniversity,Zhanjiang524001,China)[Abstract]1ObjectiveToexploretheimpactofpropofolcombinedwithremifentaniltarget-controlledinfusionanesthesiaonsedationeffectandagitationinpatientsundergoinglaparoscopicradicalresectionofcoloncancer.MethodsAtotalof120patientsundergoinglaparoscopicradicalresectionofcoloncancerweredividedintotwogroupsaccordingtodifferentanesthesiamethods.Thecontrolgroupwasanesthetizedwithpropofolcombinedwithsufentaniltargetcontrolledinfusion,andtheobservationgroupwasanesthetizedwithpropofolcombinedwithremifentaniltargetcontrolledinfusion.Thesedativeeffect,agitationandadversereactionswerecomparedbetweenthetwogroups.ResultsTh...
