天然产物研究与开发NatProdResDev2023,35:1431-1441,1456槟榔化学成分、药理、毒性研究进展及质量标志物预测分析策力木格",许许良2*1内蒙古民族大学蒙医药学院；²内蒙古民族大学化学与材料学院，通辽028000摘要：槟榔是我国常用的中药材，被列为四大南药之首，槟榔果实又为咀嚼嗜好品，具有广泛的药理活性又具毒性。近年来,国内外学者关于槟榔研究逐渐深入，,槟榔中化学成分类型较多,具有多种药理作用,本文对其化学成分、药理作用、毒性作用等进行归纳总结的基础上从槟榔特有化学成分、可测成分、传统药性功效、炮制对化学成分的影响、人血成分和等多个方面进行槟榔质量标志物预测分析，筛选可作为槟榔质量标志物的首选成分及备选成分。为建立槟榔质量控制与评价体系提供参考。关键词：槟榔；化学成分；药理作用；毒性作用；质量标志物中图分类号：R917D01:10.16333/j.1001-6880.2023.8.016Researchprogressinchemicalcomposition,pharmacologyandtoxicityofArecaSemenandpredictionandanalysisofitsqualitymarkers文献标识码：ACelimuge',XULiang".2*文章编号：1001-6880(2023)8-1431-12'MongolianMedicalCollege,InnerMongoliaMinzuUniversity;2CollegeofChemistryandMaterialsScience,InnerMongoliaMinzuUniversity,Tongliao028000,ChinaAbstract:ArecaeSemenisacommonlyusedChineseherbalmedicineinChina,andislistedasthefirstofthefoursouthernmedicines.Arecanutisalsoachewinghobby,whichhasawiderangeofpharmacologicalactivitiesandtoxicity.Inrecentyears,domesticandforeignscholarshavegraduallydeepenedtheirresearchonArecaeSemen.Therearemanytypesofchemi-calcomponentsinArecaeSemen,whichhaveavarietyofpharmacologicaleffects.Basedonthesummaryofitschemicalcom-ponents,pharmacologicaleffects,toxiceffects,clinicalapplications,andconsumption,thispaperanalyzesthespecificchemicalcomponents,measurablecomponents,traditionalmedicinalefficacy,theimpactofprocessingonchemicalcomponentsThebloodcomponentswereusedtopredictandanalyzethequalitymarkersofArecaeSemen,andthepreferredandalternativecomponentsofArecaeSemenqualitymarkerswerescreened.Itprovidesreferenceforestablishingqualitycontrolandevalua-tionsystemofArecaeSemen.Keywords:ArecaeSemen;chemicalcomposition;pharmacologicalaction;toxic...
