第42卷第4期2022年12月Vol.42，No.4Dec.2022化学传感器CHEMICALSENSORSL-半胱氨酸光学传感器研究与应用邓威森1†，肖国强1†，袁俊1，张慢乐2*，吴玲1，曹忠1*（1.长沙理工大学化学化工学院，电力与交通材料保护湖南省重点实验室，细胞化学湖南省重点实验室，长沙410114）（2.重庆市计量质量检测研究院，重庆401123）摘要：L-半胱氨酸（L-Cys）是含巯基的小分子氨基酸之一，在许多生理和病理过程中发挥关键作用，监测L-Cys水平对临床诊断和了解人体必要的生理过程至关重要。因此，开发准确、简单、快速的L-Cys检测方法受到研究者们的广泛关注。该文介绍了近年来光学传感器在检测L-Cys中的应用，着重介绍了不同种类纳米材料构建的L-Cys比色传感器与不同分子探针构建的L-Cys荧光传感器，并对比了不同比色传感器与不同荧光传感器的检测性能。关键词：L-半胱氨酸；比色传感器；荧光传感器；纳米材料；分子探针；应用ResearchandapplicationondevelopingcolorimetricandfluorescentsensorsforL-cysteineDengWei-sen1†,XiaoGuo-qiang1†,YuanJun1,ZhangMan-le2*,WuLing1,CaoZhong1*（1.HunanProvincialKeyLaboratoryofMaterialsProtectionforElectricPowerandTransportation&HunanProvincialKeyLaboratoryofCytochemistry,SchoolofChemistryandChemicalEngineering,ChangshaUniversityofScienceandTechnology,Changsha410114，China）（2.ChongqingAcademyofMetrologyandQualityInspection,Chongqing401123，China）Abstract:L-cysteine(L-Cys)isoneofthesmallsulfhydryl-containingaminoacidsthatplaysakeyroleinmanyphysiologicalandpathologicalprocesses,whichisessentialonmonitoringL-Cyslevelsforclinicaldiagnosisandunderstandingofphysiologicalprocessesinthehumanbody.Therefore,thedevelopmentofaccurate,simple,andrapidL-Cysassayshasreceivedalotofattentionfromresearchers.ThispaperintroducestheapplicationofopticalsensorsinthedetectionofL-Cysinrecentyears,focusingonL-CyscolorimetricsensorsconstructedbydifferentkindsofnanomaterialsandL-Cysfluorescentsensorsconstructedbydifferentmolecularprobes,andcomparisonwiththedetectionperformanceofdifferentcolorimetricsensorsanddifferentfluorescentsensors.Keywords:L-cysteine;colorimetricsensors;fluorescentsensors;nanomaterials;molecularprobes;applications基...
