论著doi:10.134(-108X.2023.08.01138儿科药学杂志2023年第29卷第8期JournalofPediatricPharmacy2023Vol.29,No.81例颅内皮氏罗尔斯顿菌合并血流瓦氏葡萄球菌感染患儿的抗感染治疗张宏"，赵菲菲²，叶飞妤"，李莎"，李明（1.贵州省人民医院，贵阳550002；2.贵阳市第一人民医院，贵阳550000;3.贵州医科大学附属医院，贵阳550001)【摘要]目的：探讨1例颅内泛耐药皮氏罗尔斯顿菌合并血流瓦氏葡萄球菌感染患儿的抗感染治疗。方法：从抗感染治疗方案的制定、调整、血药浓度监测、不良反应监护等多个方面对患者实施全流程药学监护。结果：临床医师完全采纳临床药师的抗感染方案并取得了良好疗效，脑脊液和血液均未再培养出该病原菌。结论：该抗感染方案安全、有效，临床药师提供的药学服务在临床治疗中发挥着重要作用。【关键词]皮氏罗尔斯顿菌；瓦氏葡萄球菌；颅内感染；血流感染；泛耐药[中图分类号]R969.3[文献标识码]A[文章编号]1672-108X(2023)08-0038-04Anti-InfectiveTreatmentofaChildwithIntracranialInfectionofRalstoniaPickettiandBloodstreamInfectionofStaphylococcusWarneriZhangHong’,ZhaoFeifei?,YeFeiyu',LiSha',LiMing(1.GuizhouProuincialPeople'sHospital,Guyang550002,China;2.TheFirstPeople'sHospitalofGuiyang,Guiyang550000,China;3.TheAffliatedHospitalofGuizhouMedicalUniversity,Guiyang550001,China)[AbstractJObjective:Toprobeintotheanti-infectivetreatmentofachildwithintracranialinfectionofRalstoniapickettiandbloodstreaminfectionofStaphylococcuswarneri.Methods:Thewholeprocessofpharmaceuticalcarewascarriedoutfromformulationandadjustmentofanti-infectiveregimen,monitoringofbloodconcentrationandmonitoringofadversedrugreactions.Results:Thecliniciansfullyadoptedtheanti-infectiveregimenbytheclinicalpharmacistsandachievedgoodresults,withnofurtherculturesofpathogeninthecerebrospinalfluidandblood.Conclusion:Theanti-infectiveregimenissafeandeffective,andthepharmaceuticalcareprovidedbyclinicalpharmacistsplaysanimportantroleinclinicalcare.[Keywords]Ralstoniapickettii;Staphylococcuswarneri;intracranialinfection;bloodstreaminfection;extensivedrugresistant病原菌侵袭中枢神经系统可造成神经功能严重损害,甚至导致患者死亡"]。神经外科患者病情重、侵人性操作多、手术...
