2023年2月第30卷第2期微创颅内血肿清除术对高血压脑出血患者神经功能和血清炎性因子水平的影响王振华，郭效东*，杨新超，许鹏，路小奇（中国人民解放军联勤保障部队第九八八医院神经外科，河南郑州450042）【摘要】目的探讨微创颅内血肿清除术对高血压脑出血患者神经功能和血清炎性因子水平的影响。方法选取2020年10月至2021年10月我院收治的53例高血压脑出血患者，随机分为实验组（n＝27）和对照组（n＝26）。对照组采用开颅血肿清除术治疗，实验组采用微创颅内血肿清除术治疗。比较两组的神经功能及血清炎性因子水平。结果术后7天、术后1个月、术后3个月，实验组的NIHSS评分均低于对照组（P＜0．05）。术后第7天，实验组的血清IL－6、TNF－α水平均低于对照组（P＜0．05）。结论微创颅内血肿清除术可有效减轻高血压脑出血患者的神经功能受损程度，降低术后炎性因子水平。【关键词】微创颅内血肿清除术；高血压脑出血；神经功能；炎性因子中图分类号：R743.2文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.02.0211ImpactofMinimallyInvasiveIntracranialHematomaRemovalonNeurologicalFunctionandLevelsofSerumInflammatoryFactorsofPatientswithHypertensiveCerebralHemorrhage//WANGZhenhua,GUOXiaodong*,YANGXinchao,XUPeng,LUXiaoqi(DepartmentofNeurosurgery,the988thHospitaloftheJointLogisticsSupportForceoftheChinesePeople'sLiberationArmy,Zhengzhou450042,China;*Correspondingauthor:GUOXiaodong,E-mail:yimin_cch@163.com)[Abstract]ObjectiveToexploretheimpactofminimallyinvasiveintracranialhematomaremovalonneurologicalfunctionandlevelsofseruminflammatoryfactorsofpatientswithhypertensivecerebralhemorrhage.Methods53patientswithhypertensivecerebralhemorrhageadmittedtoourhospitalfromOctober2020toOctober2021wereselectedandrandomlydividedintotheexperimentalgroup(n=27)andthecontrolgroup(n=26).Thecontrolgroupwastreatedwithcraniotomyhematomaremoval,andtheexperimentalgroupwastreatedwithminimallyinvasiveintracranialhematomaremoval.Theneurologicalfunctionandlevelsofseruminflammatoryfactorswerecomparedbetweenthetwogroups.ResultsAt7days,1monthand3monthsaftersurgery,theNIHSSscoresintheexperimentalgroupwerelowerthanthoseinthecontrolgroup(P<0.05).Atthe7thdayaftersurgery,thele...
