2023年4月第30卷第4期右美托咪定全麻输注对髋关节置换术患者镇静深度及血流动力学的影响分析张金雄,张孝华(茂名市中医院手术麻醉科,广东茂名525000)【摘要】目的探讨右美托咪定全麻输注对髋关节置换术患者镇静深度及血流动力学的影响。方法选取我院2020年1月至12月收治的50例髋关节置换术患者,随机分为两组。对照组接受常规麻醉,研究组接受右美托咪定全麻输注。比较两组的镇静深度以及血流动力学指标。结果研究组的首次睁眼时间、术后拔管时间、PACU停留时间均短于对照组,苏醒时BIS高于对照组(P<0.05)。麻醉诱导后30min(T30min),研究组的血流动力学指标(SaO2、HR、MAP)变化幅度均小于对照组(P<0.05)。结论右美托咪定全麻输注应用于髋关节置换术患者的麻醉效果显著,血流动力学稳定性高。【关键词】右美托咪定;全麻输注;髋关节置换术;镇静深度;血流动力学中图分类号:R614.2文献标识码:Adoi:10.3969/j.issn.1674-4659.2023.04.0509AnalysisontheImpactofDexmedetomidineGeneralAnesthesiaInfusiononSedationDepthandHemodynamicsinPatientswithHipReplacement//ZHANGJinxiong,ZHANGXiaohua(DepartmentofSurgicalAnesthesiology,MaomingHospitalofTraditionalChineseMedicine,Maoming525000,China)[Abstract]ObjectiveToexploretheimpactofdexmedetomidinegeneralanesthesiainfusiononsedationdepthandhemodynamicsinpatientswithhipreplacement.Methods50patientswithhipreplacementadmittedtoourhospitalfromJanuary2020toDecember2020wererandomlydividedintotwogroups.Thecontrolgroupreceivedroutineanesthesia,andthestudygroupreceiveddexmedetomidinegeneralanesthesiainfusion.Thesedationdepthandhemodynamicindicatorswerecomparedbetweenthetwogroups.ResultsThefirsteyeopeningtime,postoperativeextubationtimeandPACUstaytimeinthestudygroupwereshorterthanthoseinthecontrolgroup,andBISatwakingwashigherthanthatinthecontrolgroup(P<0.05).At30minafteranesthesiainduction(T30min),thechangesofhemodynamicindicators(SaO2,HR,MAP)inthestudygroupweresmallerthanthoseinthecontrolgroup(P<0.05).ConclusionsDexmedetomidinegeneralanesthesiainfusionappliedinpatientswithhipreplacementhassignificantanestheticeffectandhighhemodynamicstability.[Keywords]Dexmedetomidine;Generalanesthesiainfusi...