·论著·503中国医刊2023年第58卷第5期[12]LIH,QINS,LIANGQ,etal.ExercisetrainingenhancesmyocardialmitophagyandimprovescardiacfunctionviaIrisin/FNDC5-PINK1/ParkinpathwayinMImice[J].Biomedicines,2021,9(6):701.[13]SANCHIS-GOMARF,LAVIECJ,MARÍNJ,etal.Exerciseeffectsoncardiovasculardisease:frombasicaspectstoclinicalevidence[J].CardiovascRes,2022,118(10):2253-2266.[14]KOHKW,WANGW,RICHARDSAM,etal.Effectivenessofadvancedpracticenurse-ledtelehealthonreadmissionsandhealth-relatedoutcomesamongpatientswithpost-acutemyocardialinfarction:ALTRAStudyProtocol[J].JAdvNurs,2016,72(6):1357-1367.[15]梁鹏,张明明,高蕾,等.家庭运动康复模式对经皮冠状动脉介入治疗术后患者焦虑抑郁状态的影响[J].中国医刊,2021,56(8):853-856.[16]GUAZZIM,BANDERAF,OZEMEKC,etal.Cardiopulmonaryexercisetesting:Whatisitsvalue?[J].JAmCollCardiol,2017,70(13):16-18.[17]KETEYIANSJ,BRAWNERCA,SAVAGEPD,etal.Peakaerobiccapacitypredictsprognosisinpatientswithcoronaryheartdisease[J].AmHeartJ,2008,156(2):292-300.[18]SNOEKJA,PRESCOTTEI,VANDERVELDEAE,etal.Effectivenessofhome-basedmobileguidedcardiacrehabilitationasalternativestrategyfornonparticipationinclinic-basedcardiacrehabilitationamongelderlypatientsinEurope:Arandomizedclinicaltrial[J].JAMACardiol,2021,6(4):463-468.[19]DORJET,ZHAOG,SCHEERA,etal.SMARTphoneandsocialmedia-basedCardiacRehabilitationandSecondaryPrevention(SMART-CR/SP)forpatientswithcoronaryheartdiseaseinChina:arandomisedcontrolledtrialprotocol[J].BMJOpen,2018,8(6):e021908.[20]王隽,李刚,王沅,等.新冠肺炎疫情下互联网医院建设探讨[J].中国社会医学杂志,2022,39(1):4-6.（收稿日期：2023-01-30；修回日期：2023-03-15）（本文编辑：安静）优化比伐芦定抗凝方案应用于老年急性心肌梗死急诊经皮冠状动脉介入的临床疗效包恩泽，皮林*，贾衍尧，徐世莹，周立辉，齐冰洋（北京市垂杨柳医院心内科，北京100022）摘要：目的分析老年急性心肌梗死患者行急诊经皮冠状动脉介入时应用优化比伐芦定抗凝方案的临床疗效及安全性。方法选择2020年8月至2021年8月在北京市垂杨柳医院行急诊经皮冠状动脉介入治疗的老年急性心肌梗死患者84例，采用随机数字表法分为普通肝素组和优化比伐芦...
