2023年2月第30卷第2期右美托咪定联合咪达唑仑经鼻滴注在小儿静吸复合全麻的临床应用朱志富1，杨土炯2，黄水洋3（茂名市茂南区人民医院1手术麻醉科，2麻醉科，3药剂科，广东茂名525011）【摘要】目的探讨右美托咪定联合咪达唑仑经鼻滴注在小儿静吸复合全麻的应用效果。方法60例外科手术患儿随机分为两组。麻醉前15min，对照组给予生理盐水经鼻滴注，观察组给予右美托咪定联合咪达唑仑混合液经鼻滴注。比较两组的临床指标、麻醉躁动情况及疼痛程度。结果观察组T1和T2时的HR、收缩压、舒张压均低于对照组（P＜0.05）。两组的PAED和FLACC疼痛评分均随着恢复时间的延长而降低（P＜0.05），观察组t1、t2、t3时的PAED评分和FLACC疼痛评分均低于对照组（P<0.05）。结论经鼻滴注右美托咪定联合咪达唑仑用于小儿静吸复合全麻的镇静效果较佳，可改善患儿的躁动情况，降低患儿的疼痛感。【关键词】右美托咪定；咪达唑仑；经鼻滴注；小儿静吸复合全麻中图分类号：R614.2文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.02.0177ClinicalApplicationofDexmedetomidineCombinedwithMidazolambyNasalDripinPediatricIntravenousInhalationCombinedGeneralAnesthesia//ZHUZhifu1,YANGTujiong2,HUANGShuiyang3(1DepartmentofSurgicalAnesthesiology,2De-partmentofAnesthesiology,3DepartmentofPharmacy,MaomingMaonanDistrictPeople'sHospital,Maoming525011,China)[Abstract]ObjectiveToexploretheapplicationeffectofdexmedetomidinecombinedwithmidazolambynasaldripinpediatricintravenousinhalationcombinedgeneralanesthesia.Methods60casesofsurgicalchildrenwererandomlydividedintotwogroups.15minbeforeanesthesia,thecontrolgroupwasgivensalinebynasaldrip,theobservationgroupwasgivendexmedetomidinecombinedwithmidazolambynasaldrip.Theclinicalindicators,anesthesiaagitationandpaindegreewerecomparedbetweenthetwogroups.ResultsTheHR,systolicbloodpressureanddiastolicbloodpressureatT1andT2oftheobservationgroupwerelowerthanthoseofthecontrolgroup(P<0.05).ThePAEDandFLACCpainscoresofthetwogroupsdecreasedwiththeprolongationofrecoverytime(P<0.05);ThePAEDandFLACCpainscoresatt1,t2andt3oftheobservationgroupwerelowerthanthoseofthecontrolgroup(P<0.05).ConclusionsDexmedetomidinecombinedwithmidazolambynasaldripappliedinpe...
