三阴性乳腺癌的MRI研究新进展李建斌,徐华春,伍满香,李强宁波大学附属人民医院医学影像科浙江宁波315100【摘要】三阴性乳腺癌是乳腺癌特殊病理亚型,不表达雌激素受体、孕激素受体和人类表皮生长因子受体-2,因此可选择的临床治疗手段不多。该肿瘤侵袭性强,易复发和转移,预后较差。早期诊断和精准评估对该肿瘤的治疗有重要临床价值。MRI因其较高的软组织分辨率、多序列多方位成像特点、动态血流灌注等优势是目前乳腺癌的常用影像学检查方法。近年来MRI对三阴性乳腺癌的诊断和评估有了进一步的发展。本文就此做一综述,旨在提高对该检查的认识。【关键词】三阴性乳腺癌;磁共振成像;影像组学中图分类号:R445.2;R737.9文献标识码:A文章编号:1006-9011(2023)04-0648-04NewprogressinMRIdiagnosisoftriple-negativebreastcancerLIJianbin,XUHuachun,WUManxiang,LIQiangDepartmentofRadiology,TheAffiliatedPeople’sHospitalofNingboUniversity,Ningbo315100,China【Abstract】Triple-negativebreastcancerisaspecialpathologicalsubtypeofbreastcancer,whichdoesnotexpressestrogen,progesteronereceptorandhumanepidermalgrowthfactorreceptor-2,sotherearenotmanyoptionsforclinicaltreatment.Thetumorishighlyinvasive,pronetorecurrenceandmetastasis,andhasapoorprognosis.Earlydiagnosisandaccurateassessmenthaveimportantclinicalvalueinthetreatmentofthistumor.Duetoitshighsofttissueresolution,multi-sequenceandmulti-direc-tionalimagingcharacteristics,anddynamicbloodperfusion,MRIiscurrentlyacommonlyusedimagingmethodforbreastcancer.Inrecentyears,MRhasfurtherdevelopedinthediagnosisandevaluationoftriple-negativebreastcancer.Thisarticlemakesare-viewonthis,aimingtoraiseawarenessoftheinspection.【Keywords】Triple-negativebreastcancer;Magneticresonanceimaging;Radiomics乳腺癌(breastcancer,BC)发病率占我国恶性肿瘤的第四位[1],目前已超过肺癌成为增长最快的恶性肿瘤[2]。BC的相关致死率近年来也明显升高[3]。三阴性乳腺癌(threenegativebreastcancer,TNBC)是一种特殊病理亚型的BC,约占全部BC的10%~20%,但占转移性乳腺癌的50%[4]。该肿瘤具有发病年龄早、临床分期晚、组织学级别高、易于局部复发和转移等特点。肿瘤内部异质性高,不表达雌激素受体(estroge...