《电子技术应用》2023年第49卷第3期健康医疗微电子MicroelectronicsinMedicalandHealthcare技术专栏技术专栏丨特约主编黄成军刘欢朱疆凝血功能物理检测方法的研究进展*汤赟,朱疆,张玉仙,张帆(北京信息科技大学光电测试技术及仪器教育部重点实验室,北京100192)摘要:凝血功能的评估有助于诊断血液疾病,指导心脑血管疾病的治疗,评估手术中出血的风险。基于物理方法的凝血检测因其检测时间快、灵敏度高、操作简便等优点备受临床医学的关注。近年来,随着光学相干层析成像(OpticalCoherenceTomography,OCT)技术的进步,OCT技术开始应用于凝血检测中。对近年来物理方法在凝血检测中的应用进行了综述,重点分析了OCT技术在凝血检测中的应用,并对未来凝血检测方法的发展做出展望。关键词:凝血检测;光学相干层析成像;血液粘弹性中图分类号:TH776;O59文献标志码:ADOI:10.16157/j.issn.0258-7998.223553中文引用格式:汤赟,朱疆,张玉仙,等.凝血功能物理检测方法的研究进展[J].电子技术应用,2023,49(3):21-29.英文引用格式:TangYun,ZhuJiang,ZhangYuxian,etal.Progressonphysicalmethodsforbloodcoagulationdetection[J].Ap‐plicationofElectronicTechnique,2023,49(3):21-29.ProgressonphysicalmethodsforbloodcoagulationdetectionTangYun,ZhuJiang,ZhangYuxian,ZhangFan(KeyLaboratoryoftheMinistryofEducationforOptoelectronicMeasurementTechnologyandInstrument,BeijingInformationScienceandTechnologyUniversity,Beijing100192,China)Abstract:Theassessmentofcoagulationcanhelpdiagnoseblooddiseases,guidetreatmentofcardiovasculardiseases,andas‐sessriskofbleedingduringsurgery.Physicalcoagulationtestingisofgreatinteresttoclinicalmedicinebecauseofitsshortdetec‐tiontime,highsensitivity,andsimpleoperation.Withtherapiddevelopmentofopticalcoherencetomography(OCT)technology,ithasbeenusedinthebloodcoagulationdetection.Inthispaper,wesummarizethephysicalmethodsforthebloodcoagulationdetectioninrecentyearsandspeciallyreviewtheapplicationsoftheOCTmethodsinthecoagulationtesting.Thefuturedevelop‐mentofbloodcoagulationdetectionisalsoprospected.Keywords:bloodcoagulationdetection;opticalcoherencetomography;bloodviscoelasticity0引言内稳态是所有脊椎动物的一...