20232023年3月第54卷第3期年3月第54卷第3期216综合病例研究综合病例研究新医学新医学母细胞性浆细胞样树突状细胞肿瘤伴急性髓系白血病一例孔利华秦丽莉冯安华刘真真唐娜臧继康王海英【摘要】母细胞性浆细胞样树突状细胞肿瘤（BPDCN）伴急性髓系白血病（AML）罕见，该文报道了1例以发热为首发症状的BPDCN伴AML患者的诊治过程以提高临床医师的诊治水平。该例患者为69岁男性，因发热1周入院，无典型的皮肤损害表现，骨髓涂片细胞形态学分析示增生极度活跃，且瘤细胞免疫表型独特，确诊为BPDCN伴AML。建议其选择含维奈克拉的低强度化学治疗方案，但患者放弃治疗。【关键词】母细胞性浆细胞样树突状细胞肿瘤；急性髓系白血病；诊断；治疗Blasticplasmacytoiddendriticcellneoplasmcomplicatedwithacutemyeloidleukemia:acasereportKongLihua，QinLili，FengAnhua，LiuZhenzhen，TangNa，ZangJikang，WangHaiying.AffiliatedHospitalofWeifangMedicalUniversity，SchoolofClinicalMedicine，Weifang261000，ChinaCorrespondingauthor，WangHaiying，E-mail:wanghaiying1121@126.com【Abstract】Blasticplasmacytoiddendriticcellneoplasm（BPDCN）complicatedwithacutemyeloidleukemia（AML）isararedisease.Inthisarticle，wereportedthediagnosisandtreatmentofonepatientofBPDCNcomplicatedwithAMLwhopresentedwithfeverasthefirstsymptom，aimingtoenhancethediagnosticandtherapeuticcapabilityofcliniciansforthisdisease.Themalepatient，aged69yearsold，wasadmittedtohospitalduetofeverfor1week.Hehadnotypicalskinlesions.Morphologicalandcytologicalobservationofbonemarrowsmearshowedextremelyactivehyperplasiaandtumorcellswithspecificimmunophenotype.ThediagnosisofBPDCNcomplicatedwithAMLwasconfirmed.Alow-intensityvenetoclax-basedchemotherapyregimenwasrecommended.However，thepatientdiscontinuedfurthertreatment.【Keywords】Blasticplasmacytoiddendriticcellneoplasm；Acutemyeloidleukemia；Diagnosis；Treatment作者单位：261000潍坊，潍坊医学院附属医院（临床医学院）（孔利华，唐娜，臧继康）；261000潍坊，潍坊医学院附属医院血液科（秦丽莉，冯安华，刘真真，王海英）通信作者，王海英，E-mail:wanghaiying1121@126.comDOI:10.3969/j.issn.0253-9802.2023.03.010母细胞性浆细胞样树突状细胞肿瘤（BPDCN）是一种...
