2023年第4期广东化工第50卷总第486期www.gdchem.com·87·一款修护舒缓乳霜的功效研究罗利，张志全，陈玉娇(广州天源生物科技有限公司，广东广州510800)[摘要]对实验室研究的一款修护舒缓乳霜功效探讨，并进行人体临床功效测试，评价其修护，褪红，舒缓功效。选择32名18~40岁敏感肌的健康志愿者作为研究对象，通过使用修护舒缓乳霜前后对比；每天2次，早晚各1次，连续使用4周，比较在使用产品前W0、使用产品W4后采用经皮水分流失仪(TewameterTM300)对比测试经皮失水率TEWL、面部图像分析仪(VISIA-CR)拍照对比脸颊红区变化、以及皮肤科医生通过对面部敏感症状评分(红斑、红疹、干燥、脱屑、水肿、丘疹等)和受试者自行评估，综合评估该产品功效。经对比发现产品连续使用4周后能明显降低皮肤受到外界刺激因素后经皮失水率TEWL，表明产品具有修护皮肤屏障功效；脸颊红区面积差异虽无显著性，但其面积占比有一定降低，表明褪红趋势有所改善；面部红斑、红疹、干燥、脱屑、水肿、丘疹等综合评估效果得到明显缓解，表明产品具有舒缓功效。[关键词]乳霜；敏感肌；经皮失水率TEWL；修护；褪红；舒缓[中图分类号]TQ[文献标识码]A[文章编号]1007-1865(2023)04-0087-05EfficacyEvaluationStudyofaRepairingandSoothingCreamLuoLi,ZhangZhiquan,ChenYujiao(GuangzhouTianYuanBiotechnologyCo.,Ltd.,Guangzhou510800,China)Abstract:Studyontheefficacyofarepairingandsoothingcreaminlaboratory,Andhumanclinicalefficacytests,Evaluateitsrepair,Fadedred,Soothingeffect.Thirty-twohealthyvolunteersaged18to40withsensitivemuscleswereselectedassubjects,Beforeandaftercomparisonbyusingrepairsoothingcream;2timesaday,Onceinthemorningandevening,Continuoususefor4weeks,Comparebeforeusingtheproduct,AfterproductW4wasused,thetransdermalwaterlossrate(TewameterTM300)wascomparedandtested,ThefacialImageAnalyzer(VISIA-CR)takespicturestocomparethechangesintheredareasofthecheeks,Andself-assessmentbydermatologistsandsubjectsonfacialsensitivityscores(erythema,rashes,dryness,desquamation,edema,papules,etc.),Comprehensivelyevaluatetheefficacyoftheproduct.Bycomparison,itwasfoundthattheproductcouldsignificantlyreducetheTEWLafter4weeksofcontinuoususe,Itindicatesthattheproducthastheeffectofrepairingskinbarrier;Therewas...
