综述|Reviews磁共振成像2023年6月第14卷第6期ChinJMagnResonImaging,Jun,2023,Vol.14,No.6http://www.chinesemri.com脊髓型颈椎病脑影像学改变的MRI研究进展吴开富,王翔*作者单位:华中科技大学同济医学院附属武汉中心医院影像科,武汉430014*通信作者:王翔,E-mail:wangxiang385@aliyun.com中图分类号:R445.2;R681.55文献标识码:ADOI:10.12015/issn.1674-8034.2023.06.034本文引用格式:吴开富,王翔.脊髓型颈椎病脑影像学改变的MRI研究进展[J].磁共振成像,2023,14(6):187-191.[摘要]脊髓型颈椎病(cervicalspondyloticmyelopathy,CSM)是一种常见的退行性疾病,对患者神经功能危害严重,一直受到临床的广泛关注。研究表明,CSM不仅会对脊髓本身造成损伤,还会引起远端大脑中枢发生重塑性改变,这可能与患者症状及预后相关。为深入了解CSM潜在的神经病理学机制,本文从多参数MRI技术(基于体素的形态学分析、扩散张量成像、功能磁共振成像、磁共振波谱等)的角度对CSM脑影像学的研究现状和进展予以综述,这将对指导临床治疗及提升远期康复疗效具有重要意义。[关键词]脊髓型颈椎病;脑重塑;基于体素的形态学测量分析;功能磁共振成像;扩散张量成像;磁共振成像ResearchprogressofMRIonbraininpatientswithcervicalspondyloticmyelopathyWUKaifu,WANGXiang*DepartmentofRadiology,theCentralHospitalofWuhan,TongjiMedicalCollege,HuazhongUniversityofScienceandTechnology,Wuhan430014,China.*Correspondenceto:WangX,E-mail:wangxiang385@aliyun.comReceived5Apr2023,Accepted2Jun2023;DOI:10.12015/issn.1674-8034.2023.06.034ACKNOWLEDGMENTSScientificResearchFoundationofWuhanCentralHospital(No.22YJ29).Citethisarticleas:WUKF,WANGX.ResearchprogressofMRIonbraininpatientswithcervicalspondyloticmyelopathy[J].ChinJMagnResonImaging,2023,14(6):187-191.AbstractCervicalspondyloticmyelopathy(CSM)isacommondegenerativediseasewithsevereneurologicalimpairment.CSMhasreceivedwidespreadclinicalattention.PreviousstudieshaveshownthatCSMnotonlycausesinjurytothespinalcorditself,butalsocausesremodelingchangesinthedistalbraincenter,whichmayberelatedtothesymptomsandprognosisofpatients.InordertofurtherunderstandthepotentialneuropathologicalmechanismofCSM,thepaperreviewsthecurrentresearchstatusandpr...