2023年4月国际神经病学神经外科学杂志Vol.50No.2第50卷第2期JournalofInternationalNeurologyandNeurosurgeryApr.2023前交通动脉瘤形态学与血流动力学研究进展汤文翔1,2,赵洋洋1,2,杨少春1,21.赣南医学院第一附属医院神经外科,江西赣州3410002.赣南医学院心脑血管疾病防治教育部重点实验室,江西赣州341000摘要:前交通动脉瘤是颅内动脉瘤中最常见的类型,一旦破裂,往往症状剧烈,预后不良。近年来,随着影像三维重建技术的发展和计算流体力学的兴起,前交通动脉瘤起始、发展、破裂过程中相关形态学特征及异常血流动力学变化逐渐被揭示。研究表明,前交通动脉瘤的最大径、纵横比、大小比等特征有助于预测破裂风险,大脑前动脉一侧A1段发育不良以及A1段、A2段夹角与前交通动脉瘤的发生发展有关,血流动力学改变在动脉瘤形成和破裂中起重要作用。该文对前交通动脉瘤形态学特征和异常血流动力学变化之间的联系进行综述,探讨两者之间相互作用的内在机制,为前交通动脉瘤的早期防治提供依据以及新的思路。[国际神经病学神经外科学杂志,2023,50(2):91-96]关键词:前交通动脉瘤;形态学;血流动力学中图分类号:R743DOI:10.16636/j.cnki.jinn.1673-2642.2023.02.019ResearchadvancesinthemorphologyandhemodynamicsofanteriorcommunicatingarteryaneurysmTANGWenxiang1,2,ZHAOYangyang1,2,YANGShaochun1,21.TheFirstClinicalSchoolofGananMedicalCollege,Ganzhou,Jiangxi341000,China2.KeyLaboratoryofMinistryofEducationforPreventionandTreatmentofCardiovascularandCerebrovascularDiseases,GannanMedicalUniversity,Ganzhou,Jiangxi341000,ChinaCorrespondingauthor:YANGShaochun,Postgraduatesupervisor,Chiefphysician,Associateprofessor,Mainlyengagedintheresearchofminimallyinvasiveinterventionaltreatmentofintracranialaneurysm,Vascularmalformationandothercere⁃brovasculardiseases,Email:yangshch680709@hotmail.comAbstract:Anteriorcommunicatingarteryaneurysmisthemostcommontypeofintracranialaneurysm,andonceruptured,itoftenleadstoseveresymptomsandpoorprognosis.Inrecentyears,withthedevelopmentofthree-dimensionalimagingreconstructionandtheemergenceofcomputationalfluiddynamics,relatedstudieshavegraduallyrevealedthemorphologicalfeaturesandabnormalhemodynamicchangesdurin...