·综述·doi:10.3969/j.issn.1671-8348.2023.08.026网络首发https://kns.cnki.net/kcms/detail//50.1097.R.20230130.1531.011.html(2023-01-31)帕金森病直立性低血压危险因素的研究进展*唐泽丽1,唐欢1综述,李娟2△,郝明青3审校(1.遵义医科大学护理学院,贵州遵义563006;2.贵州省人民医院护理部,贵阳550002;3.贵州中医药大学护理学院,贵阳550002)[摘要]帕金森病直立性低血压(PD-OH)是帕金森病的一种严重并发症,是帕金森病患者跌倒及死亡的主要原因之一,PD-OH发病机制复杂,控制致使PD-OH恶化的全身因素是减少发病率的关键。目前研究显示,PD-OH发生风险增加与多种因素有关。该文就PD-OH的相关危险因素进行综述,以期为PD-OH的研究和防治提供理论支持。[关键词]帕金森病;直立性低血压;危险因素;综述[中图法分类号]R742[文献标识码]A[文章编号]1671-8348(2023)08-1253-04ResearchprogressonriskfactorsoforthostatichypotensioninpatientswithParkinson’sdisease*TANGZeli1,TANGHuan1,LIJuan2△,HAOMingqing3(1.GraduateSchoolofZunyiMedicalUniversity,Zunyi,Guizhou563006,China;2.DepartmentofNursing,GuizhouProvincialPeople’sHospital,Guiyang,Guizhou550002,China;3.GraduateSchoolofGuizhouUniversityofTraditionalChineseMedicine,Guiyang,Guizhou550002,China)[Abstract]Parkinson’sdiseaseorthostatichypotension(PD-OH)isaseriouscomplicationofParkin-son’sdisease(PD)andalsooneofthemaincausesoffallsanddeathsinthepatientswithPD.Thepathogene-sisofPD-OHiscomplex,anditsoccurrenceriskincreaseisrelatedwiththemultiplefactors.ControllingthewholebodyfactorscausingPD-OHworsenisthekeytoreduceitsincidencerate.Thispaperreviewstherele-vantriskfactorsofPD-OHandprovidesatheoreticalsupportfortheresearch,preventionandtreatmentofPD-OH.[Keywords]Parkinson’sdisease;orthostatichypotension;riskfactors;review帕金森病(Parkinson’sdisease,PD)为中老年人常见的慢性进行性神经系统变性疾病,涉及多个神经解剖区域,临床上表现为震颤、肌张力增高、运动及姿势平衡障碍[1]。除了经典的运动症状外,非运动症状也被视为PD的重要组成部分,严重影响PD患者的生活质量[2]。有研究[3]表明,某些非运动症状可能早于运动症状发生,且对PD患者的生活质量影响更大。在这些非运动症状中,直立性低血压(orthostatichy-potension,OH)是PD患者...
