Citethis:NewCarbonMaterials,2023,38(3):496-509DOI:10.1016/S1872-5805(23)60730-9RecentdevelopmentsinMXeneandMXene/carboncompositesforuseinbiomedicalapplicationsQINMiao1,2,ChaimaMerzougui1,2,SUYi-meng1,2,LIYong-feng1,2,*,CHENWei-yi1,2,HUANGDi1,2,*（1.DepartmentofBiomedicalEngineering,ResearchCenterforNano-biomaterials&RegenerativeMedicine,ShanxiKeyLaboratoryofMaterialsStrength&StructuralImpact,CollegeofBiomedicalEngineering,TaiyuanUniversityofTechnology,Taiyuan030024,China;2.Shanxi-ZhedaInstituteofAdvancedMaterialsandChemicalEngineering,Taiyuan030032,China）Abstract：MXeneisarevolutionarytwo-dimensionalmaterialthathasadistinctlayerstructureandthechemicalcompositionoftransitionmetalcarbides.Ithasspecialphysicochemicalcharacteristicsincludingalargespecificsurfacearea,goodelectricalcon-ductivity,excellentmechanicalpropertiesandphotothermalbehavior,whichgiveitavaluablevarietyofapplications.Toendowitabroaderrangeofapplications,itisoftencompositedwithcarbon-basedmaterials.Therefore,MXeneandMXene/carboncompositeshaveattractedmuchattentioninapplicationssuchaselectronics,biosensorsandbiomedicineoverrecentyears.Inthisreview,thefabrication,modificationandbiomedicalapplicationsofMXeneandMXene/carboncompositesareintroduced,focussingontheirbiomedicalapplications,suchasbiosensors,antibacterialmaterials,drugdelivery,andthediagnosisandtreatmentofdiseases.Keywords:MXene/carbonbasedcomposites；Biomedicalapplication；Sensor；Antibacterial1IntroductionWiththeadvancementsinmaterialscience,afamilyofnovelmaterials,MXene,withtwo-dimen-sionstructureshasemerged,whichhasdrawnincreas-ingattentionfromresearchersowingtothedistinctlayerstructureandexcellentphysicochemicalproper-tiesoverthepastyears.MXeneisaseriesoftrans-itionmetalcarbides,nitridesorcarbonitrides,whosechemicalformulaareexpressedasMn+1XnTx(n=1,2,3)[1].Inthisformula,“M”representstheelementoftransitionmetal(suchasSc,It,V,Cr,Zr,Nb,Mo,HfandTa),Xstandsfortheelementsofcarbonornitro-gen,whileTistheextremitygroupwhichisbondedwithMlayer(s...
