《癌症进展》2023年3月第21卷第6期ONCOLOGYPROGRESS,Mar2023Vol.21,No.6*论著*甲状腺微小乳头状癌中央淋巴结转移的影响因素甲状腺微小乳头状癌中央淋巴结转移的影响因素孙秋红#,刘京平,娄菁,徐晓慧首都医科大学电力教学医院/国家电网公司北京电力医院肿瘤科,北京1000730摘要摘要:目的目的探讨甲状腺微小乳头状癌(PTMC)患者发生中央淋巴结转移(CLNM)的影响因素。方法方法收集804例接受甲状腺手术的PTMC患者的病历资料,分析PTMC患者发生CLNM的危险因素。结果结果804例PTMC患者中,324例(40.3%)患者发现CLNM。无CLNM和有CLNM患者性别、年龄、肿瘤直径、多灶性及存在微钙化情况比较,差异均有统计学意义(P﹤0.05)。多因素分析结果显示,男性、年龄﹤45岁、存在微钙化、多灶性均是CLNM的独立危险因素(P﹤0.05)。不具有任何一个独立危险因素的PTMC患者CLNM发生率为32.1%(80/249),明显低于至少具有一个独立危险因素患者的44.1%(245/555),差异有统计学意义(P﹤0.01)。结论结论PTMC患者发生CLNM与性别、年龄、是否存在微钙化和多灶性有关。关键词关键词:甲状腺微小乳头状癌;中央淋巴结转移;影响因素中图分类号中图分类号:R736736.1文献标志码文献标志码:AdoiAdoi:10.11877/j.issn.1672-1535.2023.21.06.14InfluencingfactorsforcentrallymphnodemetastasisinpapillarythyroidInfluencingfactorsforcentrallymphnodemetastasisinpapillarythyroidmicrocarcinomamicrocarcinomaSUNQiuhong#,LIUJingping,LOUJing,XUXiaohuiDepartmentofOncology,ElectricPowerTeachingHospitalofCapitalMedicalUniversity/BeijingElectricPowerHospitalofStateGridCorporationofChina,Beijing100073,ChinaAbstractAbstract:ObjectiveObjectiveToinvestigatetheinfluencingfactorsforcentrallymphnodemetastasis(CLNM)inpapillarythyroidmicrocarcinoma(PTMC)patients.MethodMethodThemedicalrecordsof804PTMCpatientswhounderwentthyroidsurgerywerecollected.RiskfactorsforCLNMinPTMCpatientswereanalyzed.ResultResultAmong804PTMCpatients,CLNMwasfoundin324(40.3%)patients.Therewerestatisticallysignificantdifferencesingender,age,tumordiameter,multifocality,andthepresenceofmicrocalcificationsbetweenpatientswithandwithoutCLNM(P<0.05).Multivariateanalysisshowedthatmalesex,<45yearsold,presenceofmicrocalcifications,andmul...