第41卷第2期2023年4月广东医科大学学报JOURNALOFGUANGDONGMEDICALUNIVERSITYVol.41No.2Apr.2023231mobilitygroupbox1-toll-likereceptor4-nuclearfactorκBsignallingpathway[J].ClinExpPharmacolPhysiol,2017,44(3):353-361.[17]SHIJ,YUT,SONGK,etal.Dexmedetomidineamelioratesendotoxin-inducedacutelunginjuryinvivoandinvitrobypreservingmitochondrialdynamicequilibriumthroughtheHIF-1a/HO-1signalingpathway[J].RedoxBiol,2021,41:101954.[18]MENGL,LIL,LUS,etal.TheprotectiveeffectofdexmedetomidineonLPS-inducedacutelunginjurythroughtheHMGB1-mediatedTLR4/NF-κBandPI3K/Akt/mTORpathways[J].MolImmunol,2018,94:7-17.[19]邓娟,李亚春,朱涛.右美托咪定对脂多糖诱导的脓毒症大鼠全身炎症反应和肺损伤的影响[J].临床麻醉学杂志,2017,33(9):899-903.[20]陈俊仁,谢乐华,劳期迎,等.肺保护性通气策略联合右美托咪定用于单肺通气肺癌根治术的效果[J].广东医科大学学报,2022,40(1):62-66.[21]ZHOUH,SUNJ,ZHONGW,etal.DexmedetomidinepreconditioningalleviatedmurineliverischemiaandreperfusioninjurybypromotingmacrophageM2activationviaPPARγ/STAT3signaling[J].IntImmunopharmacol,2020,82:106363.[22]ZHAIY,ZHUY,LIUJ,etal.Dexmedetomidinepost-conditioningalleviatescerebralischemia-reperfusioninjuryinratsbyinhibitingHighMobilityGroupProteinB1Group(HMGB1)/Toll-LikeReceptor4(TLR4)/NuclearFactorkappaB(NF-κB)signalingpathway[J].MedSciMonit,2020,26:e918617.[23]ZHANGYN,CHANGZN,LIUZM,etal.Dexmedeto-midinealleviatesgut-vascularbarrierdamageanddistanthepaticinjuryfollowingintestinalischemia/reperfusioninjuryinmice[J].AnesthAnalg,2021,134(2):419-431.[24]ZHAIM,KANGF,HANM,etal.Theeffectofdexme-detomidineonrenalfunctioninpatientsundergoingcardiacvalvereplacementundercardiopulmonarybypass:Adouble-blindrandomizedcontrolledtrial[J].JClinAnesth,2017,40:33-38.[25]CHOJS,SHIMJK,SOHS,etal.Perioperativedexme-detomidinereducestheincidenceandseverityofacutekidneyinjuryfollowingvalvularheartsurgery[J].KidneyInt,2016,89(3):693-700.基于Sentinel/Catalyst光学体表监测系统引导下的体表图像引导放疗技术在肿瘤放射治疗中的应用研究陈荣耀,郭顺,林远雄,罗晓,周怀恒,蓝威(广东省...