临床医学研究与实践2023年4月第8卷第12期ClinicaleffectofcompoundmoisteningdrynessantipruriticcreaminthetreatmentofsenilepruritusLONGXiongchu1,LONGMeifei1*,LIUXiaohu2,WANGMinfang1,ZHOUXiaoqing3,SUNXiaojuan1,ZHANGYuping4,ZHAOShehai5(1.theHospitalof81stGroupArmyPLA,Zhangjiakou075000;2.ZhangjiakouHospitalofTraditionalChineseMedicine,Zhangjiakou075000;3.WentangWorkersNursingHome,HebeiFederationofTradeUnions,Shijiazhuang050402;4.HebeiNorthUniversity,Zhangjiakou075000;5.MingdebeiCommunityHealthServiceCenter,QiaoxiDistrict,Zhangjiakou075000,China)ABSTRACT:ObjectiveToexploretheclinicaleffectofcompoundmoisteningdrynessantipruriticcreaminthetreatmentofsenilepruritus.MethodsFromMay1,2021toMay31,2022,100senileprurituspatientsadmittedinthegeriatricsanddermatologyclinicsofourhospitalwereselectedastheresearchobjects.Thepatientsweredividedintotreatmentgroupandcontrolgroupaccordingtotherandomnumbertablemethod,with50casesineachgroup.Onthebasisofgeneralintervention,thetreatmentgroupwastreatedwithcompoundmoisteningdrynessantipruriticcream,andthecontrolgroupwastreatedwith10%ureacream.Thepruritusscoreofpatientsofthetwogroupsbeforetreatmentandafter2and4weeksoftreatmentwerecompared;theclinicalefficacyofthetwogroupsofpatientswascompared;theoccurrenceofadversereactionsofpatientsofthetwogroupswascompared.ResultsInthetreatmentgroup,48casescompletedthewholecourseoftreatmentandfollow-up,1caselosttofollow-up,and1casewithdrewmidway.Inthecontrolgroup,46patientscompletedthewholecourseoftreatmentandfollow-up,2caseschangedtoothertreatmentdrugsduetopooritchingcontrol,1caselosttofollow-up,and1casewithdrewfromthetreatment.Beforetreatment,therewasnosignificantdifferenceinpruritusscorebetweenthetwogroups(P>0.05);after2and4weeksoftreatment,thepruritusscoreofthetreatmentgroupwaslowerthanthatofthecontrolgroup,andthedifferencewasstatisticallysignificant(P<0.05).Thetotaleffectiverateoftreatmentinthetreatmentgroupwas81.25%,andthatinthecontrolgroupwas47.83%.Thetotaleffectiverateoftreatmentinthetreatmentgroupwassi...
