2023年5月第30卷第5期沉香化滞丸联合双歧杆菌四联活菌片治疗慢性阻塞性肺疾病合并胃肠功能紊乱的临床效果周莹，齐红松（河南大学第一附属医院呼吸科，河南开封475000）【摘要】目的探讨沉香化滞丸联合双歧杆菌四联活菌片治疗慢性阻塞性肺疾病（COPD）合并胃肠功能紊乱的临床效果。方法选取80例COPD合并胃肠功能紊乱患者随机分为两组各40例。除常规治疗外，对照组采用双歧杆菌四联活菌片治疗，研究组在对照组基础上采用沉香化滞丸治疗。比较两组的治疗效果、胃肠黏膜功能及不良反应发生情况。结果研究组治疗总有效率为95．00％，高于对照组的80．00％（P＜0．05）。治疗后，研究组血清D－乳酸、内毒素水平低于对照组（P＜0．05）。治疗期间，两组均未出现明显不良反应。结论沉香化滞丸联合双歧杆菌四联活菌片治疗COPD合并胃肠功能紊乱临床效果显著，能有效改善患者胃肠黏膜功能且安全性较高，值得临床推广应用。【关键词】慢性阻塞性肺疾病；胃肠功能紊乱；沉香化滞丸；双歧杆菌四联活菌片中图分类号：R563.9文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.05.0653ClinicalEffectofChenxiangHuazhiPillsCombinedwithBifidobacteriumTetravaccineTabletsinTreatmentofChronicObstructivePulmonaryDiseaseComplicatedwithGastrointestinalDysfunction//ZHOUYing,QIHongsong(DepartmentofRespiratoryMedicine,theFirstAffiliatedHospitalofHe'nanUniversity,Kaifeng475000,China)[Abstract]ObjectiveToexploretheclinicaleffectofChenxiangHuazhiPillscombinedwithBifidobacteriumTetravaccineTabletsinthetreatmentofchronicobstructivepulmonarydisease(COPD)complicatedwithgastrointestinaldysfunction.Methods80patientswithCOPDcomplicatedwithgastrointestinaldysfunctionwereselectedandrandomlydividedintotwogroupsequally.Inadditiontoroutinetreatment,thecontrolgroupwastreatedwithBifidobacteriumTetravaccineTablets,andthestudygroupwastreatedwithChenxiangHuazhiPillsonthebasisofthecontrolgroup.Thetreatmenteffect,gastrointestinalmucosalfunctionandadversereactionswerecomparedbetweenthetwogroups.ResultsThetotaleffectiverateoftreatmentinthestudygroupwas95.00%,higherthan80.00%inthecontrolgroup(P<0.05).Aftertreatment,theserumD-lacticacidandendotoxinlevelsofthestudygroupwerelowerthanthoseofthecontrolgrou...
