99mTcO4-甲状腺显像评估分化型甲状腺癌术后残甲的价值分析郑贵文,夏志明,姚树展山东第一医科大学附属省立医院核医学科山东济南250021【摘要】目的探讨分化型甲状腺癌术后、131I治疗前99mTcO4-甲状腺显像评估残甲的临床应用价值。方法选取我科收治的56例分化型甲状腺癌患者,测定甲状腺蛋白(Tg)、甲状腺球蛋白抗体(TgAb)、促甲状腺激素(TSH),行99mTcO4-甲状腺显像、131I显像。分析99mTcO4-甲状腺显像灵敏度、特异度、准确度、阳性预测值、阴性预测值、残甲灶检出率,残甲摄鍀计数与Tg/TSH相关性。结果99mTcO4-甲状腺显像灵敏度86.79%,特异度66.67%,准确度85.71%,阳性预测值97.87%,阴性预测值22.22%,残甲灶检出率69.23%。残甲摄鍀计数与Tg/TSH显著相关(r=0.617,P<0.01)。结论分化型甲状腺癌术后、131I治疗前99mTcO4-甲状腺显像评估残甲临床应用价值较高,具有较高的灵敏度和阳性预测价值以及令人满意的残甲灶检出率。残甲摄鍀计数与Tg/TSH两者显著相关。【关键词】分化型甲状腺癌;131I治疗;99mTcO4-甲状腺显像;单光子发射计算机断层显像中图分类号:R736.1;R814.43文献标识码:A文章编号:1006-9011(2023)04-0559-04Thevalueof99mTcO4-thyroidscanindetectingremnantthyroidtissueindifferentiatedthyroidcancerZHENGGuiwen,XIAZhiming,YAOShuzhanDepartmentofNuclearMedicine,ShandongProvincialHospitalAffiliatedtoShandongFirstMedicalUniversity,Jinan250021,Chi-na【Abstract】ObjectiveToexplorethevalueof99mTcO4-thyroidscanindetectingremnantthyroidtissueinthyroidectomizeddifferentiatedthyroidcancer.Methods56patientswithdifferentiatedthyroidcanceradmittedtoourdepartmentwereselected.Tg,TgAbandTSHweredetermined,and99mTcO4-thyroidscanand131Iscanwereperformed.Thesensitivity,specificity,accu-racy,positivepredictivevalue,negativepredictivevalueanddetectionrateofremnantthyroidtissue,aswellasthecorrelationbe-tweentechnetiumresiduecountandTg/TSHof99mTcO4-thyroidscanwereanalyzed.ResultsThesensitivity,specificity,accu-racy,positivepredictivevalue,negativepredictivevalueanddetectionrateofremnantthyroidtissueof99mTcO4-thyroidscanwere86.79%,66.67%,85.71%,97.87%,22.22%and69.23%,respectively.Technetiumresiduecountsweresignificantlycorr...