www.ChinaAET.com健康医疗微电子MicroelectronicsinMedicalandHealthcare技术专栏技术专栏丨特约主编黄成军刘欢朱疆电子鼻技术检测人呼出气挥发性有机物的研究进展*陈雨璐,张丞源,郑雨澄,徐可(武汉大学生命科学学院,湖北武汉430072)摘要:挥发性有机化合物(VolatileOrganicCompounds,VOCs)不仅存在于人类生活环境中,也会在人体代谢过程中产生,人体产生的VOCs的种类和峰度与人体健康和疾病状态密切相关。近年来,通过无创检测的方式分析人体呼出气中VOCs的组分和浓度可以用来指示人体健康状态,在临床诊断和健康监测领域得到广泛关注。综述了呼出气VOCs的临床检测应用价值和常见检测方法,描述了各种方法的利弊。详细阐述了新型电子鼻技术给呼出气VOCs检测带来的革命性进展,为呼出气VOCs的高灵敏、高通量、智能化检测带来了更多可能。关键词:挥发性有机化合物;呼出气分析;疾病诊断;电子鼻中图分类号:R446.1;TP212.3;R-05文献标志码:ADOI:10.16157/j.issn.0258-7998.223587中文引用格式:陈雨璐,张丞源,郑雨澄,等.电子鼻技术检测人呼出气挥发性有机物的研究进展[J].电子技术应用,2023,49(3):2-10.英文引用格式:ChenYulu,ZhangChengyuan,ZhengYucheng,etal.Researchprogressofelectronicnoseindetectingvolatileorganiccompoundsinhumanexhaledbreath[J].ApplicationofElectronicTechnique,2023,49(3):2-10.ResearchprogressofelectronicnoseindetectingvolatileorganiccompoundsinhumanexhaledbreathChenYulu,ZhangChengyuan,ZhengYucheng,XuKe(CollegeofLifeSciences,WuhanUniversity,Wuhan430072,China)Abstract:VolatileOrganicCompounds(VOCs)arenotonlypresentinthehumanlivingconditions,butalsocanbeproducedintheprocessofhumanmetabolism.ThetypesandkurtosisofVOCsproducedbythehumanbodyarecloselyrelatedtohumanhealthanddiseasestatus.Inrecentyears,analyzingVOCscomponentsandconcentrationinhumanexhaledbreaththroughnon-invasivedetectioncanbeusedtoindicatehumanhealthstatus,whichhasbeenwidelyconcernedinthefieldofclinicaldiagnosisandhealthmonitoring.ThispaperreviewstheclinicalapplicationvalueandcommondetectionmethodsofexhaledVOCs,andelucidatesprosandconsofeachmethod.Inthispaper,therevolutionaryprogressbroughtbythenewelectronicnosetechnologytothedetectionofex...