第39卷第3期2023年3月长春中医药大学学报JournalofChangchunUniversityofChineseMedicineVol.39No.3Mar.2023—306—DOI:10.13463/j.cnki.cczyy.2023.03.017补肾填精方对围绝经期综合征患者血清性激素水平及子宫内膜厚度的影响蔡艳,张晓丹,孙琦玉*,王归雁,袁小敏,李家英,栾欣(上海中医药大学附属第七人民医院,上海200137)摘要:目的目的探讨补肾填精方对围绝经期综合征患者血清性激素水平及子宫内膜厚度的影响。方法方法选择80例围绝经期综合征患者,按随机数表法分为对照组与观察组,各40例。对照组采用激素替代疗法治疗,观察组在对照组基础上联合补肾填精方治疗,2组均连续治疗12周。观察2组治疗前后中医证候评分、血清性激素水平、改良Kupperman评分及子宫体积和子宫内膜厚度变化,对比2组总有效率和不良反应发生情况。结果结果观察组治疗后中医证候评分、改良Kupperman评分、血清FSH和LH水平均低于对照组(P<0.05);观察组治疗后血清E2、子宫内膜厚度均高于对照组(P<0.05);观察组治疗后总有效率(92.5%,37/40)明显高于对照组(75.0%,30/40)(P<0.05);治疗期间2组均未发生不良反应。结论结论补肾填精方能够调节围绝经期综合征患者血清性激素水平,提高患者子宫内膜厚度,缓解患者围绝经期症状,疗效明显,安全可靠。关键词:围绝经期综合征;补肾填精方;围绝经期症状;性激素;子宫内膜厚度中图分类号:R271文献标志码:A文章编号:2095-6258(2023)03-0306-04EffectofBushenTianjingrecipeontheserumsexhormonelevelandendometrialEffectofBushenTianjingrecipeontheserumsexhormonelevelandendometrialthicknessinpatientswithaperimenopausalsyndromethicknessinpatientswithaperimenopausalsyndromeCAIYan,ZHANGXiaodan,SUNQiyu*,WANGGuiyan,YUANXiaomin,LIJiaying,LUANXin(TheSeventhPeople'sHospitalAffiliatedtoShanghaiUniversityofTraditionalChineseMedicine,Shanghai200137,China)Abstract:ObjectiveAbstract:ObjectiveToinvestigatetheeffectoftheBushenTianjingrecipeontheserumsexhormonelevelandendometrialthicknessinpatientswithaperimenopausalsyndrome.MethodsMethodsAtotalof80patientswiththeperimenopausalsyndromewererandomlydividedintoacontrolgroupandanobservationgroup.Thecontrolgroupwastreatedwiththehormonereplacementtherapy.Onthisbasis,theobservationgroupwastreatedwiththeBushe...