收稿日期:2022-04-14作者单位:盐城市第一人民医院,江苏盐城224005*通信作者DOI:10.14053/j.cnki.ppcr.202302003基于AHP-TOPSIS法量化评价脑膜瘤切除术预防性抗菌药物合理性王阿明,尹存林,胡晔,张亚明,黄磊*[摘要]目的构建脑膜瘤切除术预防性抗菌药物评价细则,量化评价该类手术预防性抗菌药物使用合理性。方法依据指南及文献建立脑膜瘤切除术预防性抗菌药物评价细则,采用AHP-TOPSIS法对盐城市第一人民医院2020年1月至2021年12月收治入院的行脑膜瘤切除术的患者预防性抗菌药物使用病例的合理性进行量化评价。结果评价细则分为11个二级评价指标,其中权重较高的是药品选择、用法用量及术前用药时机(0.266、0.146、0.185)。点评的82份病例中,合理37例(45.12%),基本合理16例(19.51%),不合理29例(35.37%)。结论采用AHP-TOPSIS法对脑膜瘤切除术预防性抗菌药物进行点评,可使点评方式更加层次化、系统化,并且可操作性更强,可以在外科手术患者药物点评中广泛使用。[关键词]脑膜瘤;抗菌药物;合理用药;层次分析法;逼近理想解排序法EvaluationoftherationalityofprophylacticantibioticsinmeningiomaresectionbasedonAHP-TOPSISquantitativeanalysisWangAming,YinCunlin,HuYe,ZhangYaming,HuangLei*(YanchengNO.1People'sHospital,Yancheng224005,China)*Correspondingauthor[Abstract]ObjectiveToestablishthedetailedrulesfortheevaluationofprophylacticantibioticsinmeningio-maresectionandquantitativelyevaluatetherationalityoftheuseofprophylacticantibioticsinthiskindofsurgery.MethodsAccordingtotheguidelinesandliteratures,thedetailedrulesfortheevaluationofprophylacticantibacterialdrugsformeningiomaresectionwereestablished,andtherationalityofprophylacticantibacterialdruguseinpatientsundergoingmeningiomaresection,whowereadmittedtotheFirstPeople'sHospitalofYanchengfromJanuary2020toDecember2021,wasquantitativelyevaluated.ResultsTherewereatotalof11secondaryevaluationindicators,ofwhichthedrugselection,usageandpreoperativemedicationtimingaccountedforthehigherweight(0.266,0.146and0.185).Ofthe82casesreviewed,37(45.12%)werereasonable,16(19.51%)werebasicallyreasonable,and29(35.37%)wereunreasonable.ConclusionUsingAHP-TOPSIStoevaluatetheuseofprophy...