本期部分研究论文和研究简报的图文摘要.pdf

One-pot synthesis of(E)-diethyl 2-styrylquinoline-3,4-di-carboxylate derivativesZhao Di,Liu Yanying,Wang Yang,Li YangChemistry(Huaxue Tongbao),2023,86(5):589597A simple and flexible synthesis of a series of novel(E)-di-ethyl 2-styrylquinoline-3,4-dicarboxylates with good yields has been achieved,involving one-pot sequential Arbuzov/Horner-Wadsworth-Emmons(HWE)reaction sequence using diethyl 2-(bromomethyl)quinoline-3,4-dicarboxylate as substrate.Synthesis and antitumor activity of 2-aryl-4-trifluorom-ethylquinazoline derivativesChen Mingxiu,Cheng Sha,Dai Xing,Meng Xueling,Xu Guangcan,Xu BixueChemistry(Huaxue Tongbao),2023,86(5):598606A series of novel 2-aryl-4-trifluoromethylquinazolined-erivatives were synthesized starting from 5-chloro-2-nitro-benzoic acid by hydrolysis,reduction,coupling,cyclization,trifluoromethyl addition,and elimination reactions.Some target compounds showed inhibitory effect on five human cancer cell lines(PC3,LNCaP,K562,HeLa and A549)at 5 mol L-1.A new strategy for the construction of phosphoyl methyl-ene derivatives containing indole skeletonsFu Jianping,Xu Changjiang,Xia Jun,Han XiaodanChemistry(Huaxue Tongbao),2023,86(5):624629A series of phosphoryl methylene compounds containing in-dole skeleton were successfully obtained by addition reaction between indole enoyl compounds and diphenylphosphine ox-ide in the presence of base.The method exhibits many ad-vantages such as low temperature,high yield,rapid response etc.315http:/www.hxtb.org化学通报2023 年 第 86 卷 第 5 期