Science 2016-08-19.pdf

19 AUGUST 2016 VOL 353 ISSUE 6301 725SCIENCE sciencemag.org19 AUGUST 2016 VOLUME 353 ISSUE 6301CONTENTS754&808Better-ordered structuresNEWSIN BRIEF732 News at a glanceIN DEPTH 735 A DEBRIS-DAMMED LAKE THREATENS A FLOODEngineers ponder fixes to Spirit Lake,bottled up 36 years ago by Mount St.Helens By R.F.Service736 BONES RECORD DEMISE OF ANDEAN STATEViolent death surged as drought and political turmoil doomed the Wari By L.Wade738 NEW POLIO CASES IN NIGERIA SPUR MASSIVE RESPONSECountrys hopes for polio-free status are dashed By L.Roberts739 MISSION POSSIBLE:REWRITING THE GENETIC CODEA research team is making steady progress at overhauling a bacteriums genome By J.Bohannon REPORT P.819740 CHEMISTS TO GET PREPRINT SERVER OF THEIR OWNAmerican Chemical Society launches ChemRxiv despite dubious precedents By P.Voosen738INSIGHTSPOLICY FORUM746 BRAZILIAN POLITICS THREATENENVIRONMENTAL POLICIESThe countrys environmental licensing system is threatened By P.M.FearnsidePERSPECTIVES 749 THE QUEST TO BURN FAT,EFFORTLESSLY AND SAFELYAn enzyme steps up to BAT as a potential mitochondrial uncoupler By W.Fan and R.Evans750 DIAGNOSTICS FORZIKA VIRUS ON THE HORIZONThe immune response to Zika virus informs antibody-based diagnostics and therapeutics By S.D.Speer and T.C.Pierson REPORT P.823752 THERMALIZATION IN SMALL QUANTUM SYSTEMSA small closed quantum many-body system shows evidence of thermalization By A.Polkovnikov and D.Sels RESEARCH ARTICLE P.794SPECIAL SECTIONNeuroimmunologyINTRODUCTION 760 Immune cells on the brainNEWS762 Wired By E.UnderwoodREVIEWS766 Multifaceted interactions between adaptive immunity and the central nervous system J.Kipnis772 Maternal immune activation:Implications for neuropsychiatric disorders M.L.Estes and A.K.McAllister777 How neuroinflammation contributes to neurodegeneration R.M.RansohoffPERSPECTIVE783 Inflammatory neuroprotection following traumatic brain injury M.V.Russo and D.B.McGavernON THE COVERResident immune cells in the brain,called microglia(purple),interact with neurons(yellow).The field of neuroimmunology has captivated a growing number of researchers as connections emerge between the bodys defenses and the central nervous system.Immune cells in the brain play a role in many diseases but are also increasingly seen as central to normal brain development and function.See page 760.Illustration:Valerie Altounian/ScienceFEATURES 741 OF MICE AND MICROBESThe zoo of bacteria and viruses each lab animal harbors may confound experiments By K.Servick PODCAST744 TIGER LANDChinas first national parks include a refuge for the worlds largest cat By K.McLaughlinSEE ALSO RESEARCH ARTICLE P.789Published by AAAS on September 1,2016http:/science.sciencemag.org/Downloaded from PHOTO(RIGHT):CHRIS TZAROS19 AUGUST 2016 VOL 353 ISSUE 6301 727SCIENCE sciencemag.orgCONTENTS750&823Analyzing antibodies against Zika virus 19 AUGUST 2016 VOLUME 353 ISSUE 6301RESEARCHIN BRIEF 786 From Science and other journalsRESEARCH ARTICLES 789 IMMUNOGENOMICSMicroglia development follows a stepwise program to regulate brain homeostasis O.Matcovitch-Natan et al.RESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aad8670 NEUROIMMUNOLOGY SECTION P.760790 ECONOMICSCombining satellite imagery and machine learning to predict poverty N.Jean et al.PERSPECTIVE P.753794 STATISTICAL PHYSICSQuantum thermalization through entanglement in an isolated many-body system A.M.Kaufman et al.PERSPECTIVE P.752REPORTS 800 GEOMORPHOLOGYNorthward migration of the eastern Himalayan syntaxis revealed by OSL thermochronometry G.E.King et al.804 SEPARATION MEMBRANESReverse osmosis molecular differentiation of organic liquids using carbon molecular sieve membranes D.-Y.Koh et al.808 CRYSTALLOGRAPHYCoordinative alignment of molecules in chiral metal-organic frameworks S.Lee et al.PERSPECTIVE P.754812 BEHAVIORAL ECOLOGYPrenatal acoustic communication programs offspring for high posthatching temperatures in a songbird M.M.Mariette and K.L.Buchanan VIDEO814 GENE REGULATIONIntegration of omic networks in a developmental atlas of maize J.W.Walley et al.819 SYNTHETIC GENOMICSDesign,synthesis,and testing toward a 57-codon genome N.Ostrov et al.NEWS STORY P.739823 ZIKA VIRUSSpecificity,cross-reactivity,and function of antibodies elicited by Zika virus infection K.Stettler et al.PERSPECTIVE P.750827 HUMAN GENETICSCardiometabolic risk loci share downstream cis-and trans-gene regulation across tissues and diseases O.Franzn et al.SCIENCE(ISSN 0036-8075)is published weekly on Friday,except the last week in December,by the American Association for the Advancement of Science,1200 New York Avenue,NW,Washington,DC 20005.Periodicals mail postage(publication No.484460)paid at Washington,DC,and additional mailing offices.Copyright 2016 by the American Association for the Advancement of Science.The title SCIENCE is a registered trademark of the AAAS.Domestic individual membership and subscription(51 issues):$165($74 allocated to subscription).Domestic institutio