19AUGUST2016•VOL353ISSUE6301725SCIENCEsciencemag.org19AUGUST2016•VOLUME353•ISSUE6301CONTENTS754&808Better-orderedstructuresNEWSINBRIEF732NewsataglanceINDEPTH735ADEBRIS-DAMMEDLAKETHREATENSAFLOODEngineersponderfixestoSpiritLake,bottledup36yearsagobyMountSt.HelensByR.F.Service736BONESRECORDDEMISEOFANDEANSTATEViolentdeathsurgedasdroughtandpoliticalturmoildoomedtheWariByL.Wade738NEWPOLIOCASESINNIGERIASPURMASSIVERESPONSECountry’shopesforpolio-freestatusaredashedByL.Roberts739MISSIONPOSSIBLE:REWRITINGTHEGENETICCODEAresearchteamismakingsteadyprogressatoverhaulingabacterium’sgenomeByJ.Bohannon▶REPORTP.819740CHEMISTSTOGETPREPRINTSERVEROFTHEIROWNAmericanChemicalSocietylaunchesChemRxivdespitedubiousprecedentsByP.Voosen738INSIGHTSPOLICYFORUM746BRAZILIANPOLITICSTHREATENENVIRONMENTALPOLICIESThecountry’senvironmentallicensingsystemisthreatenedByP.M.FearnsidePERSPECTIVES749THEQUESTTOBURNFAT,EFFORTLESSLYANDSAFELYAnenzymestepsuptoBATasapotentialmitochondrialuncouplerByW.FanandR.Evans750DIAGNOSTICSFORZIKAVIRUSONTHEHORIZONTheimmuneresponsetoZikavirusinformsantibody-baseddiagnosticsandtherapeuticsByS.D.SpeerandT.C.Pierson▶REPORTP.823752THERMALIZATIONINSMALLQUANTUMSYSTEMSAsmallclosedquantummany-bodysystemshowsevidenceofthermalizationByA.PolkovnikovandD.Sels▶RESEARCHARTICLEP.794SPECIALSECTIONNeuroimmunologyINTRODUCTION760ImmunecellsonthebrainNEWS762WiredByE.UnderwoodREVIEWS766MultifacetedinteractionsbetweenadaptiveimmunityandthecentralnervoussystemJ.Kipnis772Maternalimmuneactivation:ImplicationsforneuropsychiatricdisordersM.L.EstesandA.K.McAllister777HowneuroinflammationcontributestoneurodegenerationR.M.RansohoffPERSPECTIVE783InflammatoryneuroprotectionfollowingtraumaticbraininjuryM.V.RussoandD.B.McGavernONTHECOVERResidentimmunecellsinthebrain,calledmicroglia(purple),interactwithneurons(yellow).Thefieldofneuroimmunologyhascaptivatedagrowingnumberofresearchersasconnectionsemergebetweenthebody’sdefensesandthecentralnervoussystem.Immunecellsinthebrainplayaroleinmanydiseasesbutare...
