1APRIL2016•VOL352ISSUE62815SCIENCEsciencemag.org1APRIL2016•VOLUME352•ISSUE6281CONTENTS35&95NursingmouseeggstomaturityNEWSINBRIEF12NewsataglanceINDEPTH15ELNIÑO’SWARMTHDEVASTATINGREEFSWORLDWIDERecentaerialsurveysofAustralia’sGreatBarrierReeffindmassivecoralbleachingByD.Normile16SANDYRIPPLESPOINTTOMARS’SPASTUniquedunefeaturesemergefromrover’scampaigninthesandByE.Hand18BRAZILBILLWOULDLEGALIZERENEGADECANCERPILLGovernmentracestoput“fosfo”throughclinicaltestingByH.Escobar19CANADIANSCIENTISTSSMILEATLIBERALS’DÉJÀVUBUDGETTrudeauoferswarmsupportforbasicresearchByW.Kondro20NO-STRINGSAWARDSATNIHDRAWCONCERNSomerecipientssaytheydidn’texpectdeepcutsinfundingByJ.KaiserFEATURES21IMMUNITYGOESLOCALSimilartolymphnodes,buttransient,tertiarylymphoidstructurescandriveimmuneresponsesByM.LeslieINSIGHTSLETTERS28NEXTGENVOICESPERSPECTIVES31MITOCHONDRIALDISEASETHERAPYFROMTHINAIR?Low-oxygentreatmentslowsneurodegenerationinamodelofamitochondrialdisorderByE.A.Shoubridge▶RESEARCHARTICLEP.5432RETHINKINGTHESN2REACTIONThegas-phasedynamicsofaparadigmorganicreactionaremorecomplexthanexpectedByJ.XieandW.L.Hase34HOWANTARCTICAGOTITSICEAcomplexsetofinteractionscausedtherapidgrowthoftheAntarcticicesheet34millionyearsagoByC.H.LearandD.J.Lunt▶REPORTP.7635NURSINGTHEOOCYTEMammalianeggcellsreceivematerialfromneighboring“nurse”cellsviabridgesandgapsByM.E.Pepling▶REPORTP.9537ANODDONEOUTAnoxygen-richwhitedwarfsetsanimportantmarkforstellarevolutionByB.Gänsicke▶REPORTP.6738ENGAGEKEYSOCIALCONCEPTSFORSUSTAINABILITYSocialindicators,bothmatureandemerging,areunderusedByC.C.Hicksetal.40COLLOIDALCRYSTALORDERINGINALIQUIDCRYSTALAnematicphasepromotestheformationofdilute,low-symmetrycolloidalcrystalsByC.Blanc▶REPORTP.6942ABRAINCONDITIONEDFORSOCIALDEFEATAbraincircuitinvertebratesdetermineswhowinsorlosesafightByL.DesbanandC.Wyart▶REPORTP.8743AlncRNALINKSGENOMICVARIATIONWITHCELIACDISEASEAlongnoncodingRNAisassociatedwithanintestinalautoimmunedisorderByM.Huarte▶REPORTP.9144GOINGWITHTHEFLOWAdesktopmachineallo...