CREDITS:(LEFTTORIGHT)(PHOTO)DUNEDINMULTIDISCIPLINARYHEALTHANDDEVELOPMENTRESEARCHUNIT,UNIVERSITYOFOTAGO;(GRAPHIC)K.SUTLIFF/SCIENCE2FEBRUARY2018•VOL359ISSUE6375493SCIENCEsciencemag.org2FEBRUARY2018•VOLUME359•ISSUE6375CONTENTS516&582Predictingimmunotherapyresponse516ENHANCINGRESPONSESTOCANCERIMMUNOTHERAPYThecapacityofantigenpresentationinfluencesresponsestocheckpointimmunotherapyByP.KvistborgandJ.W.Yewdell▶REPORTP.582517STEALTHREACTIONSDRIVINGCARBONFIXATIONNewtwiststobacterialmetabolicpathwaysthatcontributetotheglobalcarboncycleByS.W.Ragsdale▶REPORTSPP.559&563519LIGHTINGUPSUPERCONDUCTINGSTRIPESTerahertzradiationrevealspairdensitywavesinunderdopedcupratesuperconductorsByE.ErgeçenandN.Gedik▶REPORTP.575520GALAXYMOTIONSCAUSETROUBLEFORCOSMOLOGYSatellitegalaxymotionsaroundanearbygalaxyseemtobeatoddswithdarkmattermodelsByM.Boylan-Kolchin▶RESEARCHARTICLEP.534521TRACINGSINGLE-CELLHISTORIESOriginsofmutationsinsinglecellsduringhumanbraindevelopmentandagingarerevealedByJ.H.Lee▶RESEARCHARTICLEP.550;REPORTP.555POLICYFORUM523SCIENTIFICALLYASSESSIMPACTSOFSUSTAINABLEINVESTMENTSMetricscaninforminvestorswaryof“greenwashing”ByC.J.Vörösmartyetal.BOOKSETAL.526PICTURINGTHEFUTUREAnewfilmcelebratesamid-centuryillustratorwhostokedimaginationswithprescientcomicsByD.Greenbaum527THEFETISHIZATIONOFQUANTIFICATIONAhistorianexploresthedarksideofmetric-basedperformanceevaluationByT.M.Porter507ACCELERATORBOOMHONESCHINA’SENGINEERINGEXPERTISEBevyofparticleacceleratorscouldpavethewayforfuturecolliderthatwouldbeworld’slargestByD.Normile508DAMSNUDGEAMAZON’SECOSYSTEMSOFF-KILTERDeclineofgiantcatfishemblematicofhabitatfragmentationByB.Fraser▶SCIENCEADVANCESRESEARCHARTICLEBYE.P.ANDERSONETAL.10.1126/sciadv.aao1642FEATURE510HUMANNATURE,OBSERVEDFordecades,twopsychologistshavekeptwatchover1000NewZealanders,teasingoutfactorsthatshapealife’scourseByD.Starr▶PODCAST510INSIGHTSPERSPECTIVES514OUTOFBALANCEINTHEARCTICPolarbearshavehighenergyrequirementsthatrisefurtherasaresultofclimatechangeByJ.P.White...
