Science 2016-09-09.pdf

1068 9 SEPTEMBER 2016 VOL 353 ISSUE 6304sciencemag.org SCIENCE9 SEPTEMBER 2016 VOLUME 353 ISSUE 6304CONTENTS1095&1161Location influences tumor metabolismPHOTO:FARHAD BABAEINEWSIN BRIEF1074 News at a glanceIN DEPTH 1077 CAMPAIGN SETS OUT TO FIND A HOT LIMIT TO LIFEDeep-sea drilling expedition off Japan to probe microbial boundary beneath sea floor By P.Voosen1078 CANNONBALL!CHINAS MEGASPLASH IN OCEAN RESEARCHHuge new national labs research priorities remain sketchy By K.McLaughlin1079 THE ATMOSPHERES PACEMAKER SKIPS A BEATHiccup bodes wet winter weather for Europe By B.Mason1080 NO PROOF THAT PREDATOR CULLS SAVE LIVESTOCK,STUDY CLAIMSNew analysis calls for more rigorous studies By B.Goldfarb1081 ACCUSATIONS FLY AFTER BIG GATES GRANTPanel promises verdict on old dispute between WHO and the University of Oxford By K.KupferschmidtINSIGHTSBOOKS ET AL.1088 AUTUMN BOOKS TO FALL FORPERSPECTIVES 1094 ZIKA VACCINE TRIALSThere are new and familiar challenges in the race for timely and effective vaccines By M.Lipsitch and B.J.Cowling EDITORIAL P.1073;RESEARCH ARTICLE P.11291095 LOCATION,LOCATION,LOCATIONTissue of origin is important in determining how tumors rewire their metabolism By K.H.Vousden and M.Yang REPORT P.11611096 VISUALIZING EVOLUTION AS IT HAPPENSA meter-scale growth plate allows the evolution of antibiotic resistance to be tracked By L.McNally and S.P.Brown REPORT P.11471098 ASYMMETRY IN SUPRAMOLECULAR ASSEMBLYPhotoresponsive organic nanowires connect to gold nanomesh and silicon electrodes By S.Slim and F.Rosei1099 HOW DAMS CAN GO WITH THE FLOWSmall changes to water flow regimes from dams can help to restore river ecosystems By N.L.Poff and J.C.Schmidt1101 LENTIVIRAL VECTORS,TWO DECADES LATERA deadly virus became an effective gene delivery tool By L.Naldini et al.1103 AHMED H.ZEWAIL(19462016)A Nobel laureate,who pioneered femtochemistry,promoted a scientific renaissance in the Middle East By P.B.Dervan1104 DONALD A.HENDERSON(19282016)A pragmatic and tireless epidemiologist led the international eradication of smallpox By D.L.HeymannPOLICY FORUM 1105 A U.S.“CANCER MOONSHOT”TO ACCELERATE CANCER RESEARCHPatient engagement and data sharing must improve By D.S.Singer et al.LETTERS 1107 NUCLEAR ENERGY:IMPROVE COLLABORATIONBy H.Yang et al.1107 CANCEL YULINS ANNUALDOG MEAT FESTIVALBy Q.Meng et al.1108 TECHNICAL COMMENT ABSTRACTS1108 ONLINE BUZZ:BIODIVERSITY BOUNDARIESFEATURES 1083 IRANIAN SUNA fusion research program nurtured in isolation could blossom as Iran joins the ITER megaproject By R.Stone1085 A year after the deal,nuclear collaborations languishBy R.Stone1086 The reactor that triggered a nuclear crisis By R.StoneIrans tokamaks could see action in countrys budding relationship with the ITER fusion experiment.1083Published by AAAS on September 21,2016http:/science.sciencemag.org/Downloaded from 9 SEPTEMBER 2016 VOL 353 ISSUE 6304 1069SCIENCE sciencemag.org1137An electromagnetic shield1098A nanoscaffold for solar cellsScience Staff.1070New Products.1166Science Careers.1167DEPARTMENTS1073 EDITORIAL Ebola and Zika:Cautionary talesBy Michael T.Osterholm PERSPECTIVE P.1094;RESEARCH ARTICLE P.11291174 WORKING LIFENewton and the Big AppleBy E.S.LevineRESEARCHIN BRIEF 1109 From Science and other journalsREVIEWS1112 SOCIAL SCIENCESSocial and economic impacts of climate T.A.Carleton and S.M.HsiangREVIEW SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aad98371113 CLIMATE CHANGEImproving the forecast for biodiversity under climate change M.C.Urban et al.REVIEW SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aad84661116 BIOPHYSICSSingle-molecule dissection of stacking forces in DNA F.Kilchherr et al.RESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aaf55081117 MEMORYSynaptic mechanisms of pattern completion in the hippocampal CA3 network S.J.Guzman et al.1123 INHIBITORY SYNAPSESIdentification of an elaborate complex mediating postsynaptic inhibition A.Uezu et al.1129 VACCINESProtective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys P.Abbink et al.EDITORIAL P.1073;PERSPECTIVE P.1094REPORTS 1133 GEOPHYSICSLocal near instantaneously dynamically triggered aftershocks of large earthquakes W.Fan and P.M.Shearer1137 MATERIALS SCIENCEElectromagnetic interference shielding with 2D transition metal carbides(MXenes)F.Shahzad et al.1141 GEOCHEMISTRYHighly siderophile elements were stripped from Earths mantle by iron sulfide segregation D.C.Rubie et al.1144 ORGANIC CHEMISTRYDirhodium-catalyzed C-H arene amination using hydroxylamines M.P.Paudyal et al.1147 ANTIBIOTIC RESISTANCESpatiotemporal microbial evolution on antibiotic landscapes M.Baym et al.PERSPECTIVE P.10961151 INTERNET ACCESSDigital discrimination:Political bias in Internet service provision across ethnic groups N.B.Weidmann et al.ON THE COVERSchematic illustration showing three paths to a vaccine for Zika virus.The Zika epidemic has recently exploded in the Americas and has been shown to cause devastat-ing birth