Science 2018-06-29.pdf

sciencemag.org SCIENCE29 JUNE 2018 VOLUME 360 ISSUE 6396CONTENTSCREDITS:(CLOCKWISE FROM TOP)A.KITTERMAN/SCIENCE;WANG CHI LAU/EMBRYOLOGY COURSE AT THE MARINE BIOLOGICAL LABORATORY;ADAM SIMPSON/HEART AGENCYNEWSIN BRIEF1380 News at a glanceIN DEPTH 1383 RANDOM NUMBER GENERATORS GO PUBLICFree,web-based beacons could be used in commerce,politics,and science By S.Chen1384 IN NIGERIA,A BATTLE AGAINST PLAGIARISM HEATS UPYoung researchers champion good conduct and push for offenders to be punished By L.Nordling1385 NEWBORN SCREENING URGED FOR FATAL NEUROLOGICAL DISORDERDecision on spinal muscular atrophy due next week By M.Wadman1386 SEE-THROUGH SOLAR CELLS COULD POWER OFFICESSolar windows absorb ultraviolet and infrared light while letting visible light pass through By R.F.Service1387 BLOOD TEST MAY PREDICT CANCER IMMUNOTHERAPY BENEFITCounting tumor mutations could identify right treatment By K.GarberINSIGHTSPERSPECTIVES 1399 MORE FRICTION FOR POLYELECTROLYTE BRUSHESTrivalent yttrium cations increase friction greatly compared with monovalent cations By M.Ballauff REPORT P.14341400 LEARNING FROM PAST CLIMATIC CHANGES66 million years ago,sea temperatures rose rapidly as a result of environmental perturbations By C.Lcuyer REPORT P.14671376 29 JUNE 2018 VOL 360 ISSUE 6396DEPARTMENTS1379 EDITORIAL Tomorrows Earth By Jeremy Berg PERSPECTIVES 1396 TOWARD A SUSTAINABLE MATERIALS SYSTEMAn unprecedented effort is needed to achieve sustainable materials production and use By E.A.Olivetti and J.M.CullenBOOKS ET AL.1407 GETTING IT RIGHT ON GMOSA protesters change of heart sheds light on the publics reservations about genetic engineering By J.R.DinnenyLETTERS 1409 EDUCATION FOR THE FUTUREREVIEW1419 ENERGYNet-zero emissions energy systems S.J.Davis et al.REVIEW SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aas9793TOMORROWS EARTHFEATURES 1388 THE POWER OF MANYA series of simple steps can explain the momentous transition from single cells to multicellular life By E.Pennisi VIDEO1392 OPENING THE LAB DOORAfter a slew of victories by animal activists,scientists hope more candor will win public support for animal research By D.Grimm PODCAST29 JUNE 2018 VOLUME 360 ISSUE 631399&1434Ionic control of friction 1388ON THE COVERGrowing human populations are transforming our planet at an increas-ing rate,leading to climatic changes,diminished resources,and loss of biodiver-sity.Continuing on the current path is likely to endanger our own well-being and that of other species,but changing course involves tough choices.In the Tomorrows Earth special series,we explore paths to a more sustainable future.See http:/scim.ag/TomorrowsEarth.Illustration:Adam Simpson/Heart AgencyDA_0629TOC.indd 13766/27/18 10:28 AMPublished by AAASon July 1,2018 http:/science.sciencemag.org/Downloaded from 1423Spliceosome ready for action29 JUNE 2018 VOL 360 ISSUE 6396 1377SCIENCE sciencemag.org1447Watching mice seeCREDITS:(CLOCKWISE FROM TOP LEFT)BAI ET AL.;HONG ET AL.;SANDESH KADURDEPARTMENTS1478 WORKING LIFEThe cost of a career By Elise A.KikisRESEARCHIN BRIEF 1416 From Science and other journalsRESEARCH ARTICLES 1420 NEUROSCIENCEUltrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors T.Patriarchi et al.RESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aat44221421 STEM CELLSNotch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche R.Chakrabarti et al.RESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aan4153 PERSPECTIVE P.14011422 PALEOGENOMICSThe first horse herders and the impact of early Bronze Age steppe expansions into Asia P.de Barros Damgaard et al.RESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aar77111423 MOLECULAR BIOLOGYStructures of the fully assembled Saccharomyces cerevisiae spliceosome before activation R.Bai et al.1429 QUANTUM SIMULATIONSecond Chern number of a quantum-simulated non-Abelian Yang monopole S.Sugawa et al.REPORTS 1434 POLYMERSMultivalent counterions diminish the lubricity of polyelectrolyte brushes J.Yu et al.PERSPECTIVE P.13991438 BIOMIMETIC CHEMISTRYCarbonyl catalysis enables a biomimetic asymmetric Mannich reaction J.Chen et al.1442 SOLAR CELLSEnhanced photovoltage for inverted planar heterojunction perovskite solar cells D.Luo et al.1447 BIOMEDICAL MATERIALSA method for single-neuron chronic recording from the retina in awake mice G.Hong et al.1451 CONDENSED MATTERHeterogeneous to homogeneous melting transition visualized with ultrafast electron diffraction M.Z.Mo et al.1455 THERMAL CONDUCTIVITYTwo-channel model for ultralow thermal conductivity of crystalline Tl3VSe4 S.Mukhopadhyay et al.HUMAN DEMOGRAPHY1459 The plateau of human mortality:Demography of longevity pioneers E.Barbi et al.1462 Predictive modeling of U.S.health care spending in late life L.Einav et al.PODCAST1465 PSYCHOLOGYPrevalence-induced concept change in human judgment D.E.Levari et al.VIDEO1467 CLIMATE CHANGEPostimpact earliest Paleogene warming sh