Science 2018-04-27.pdf

https:/ TOP)C.BICKEL/SCIENCE;JUAN CRISTOBAL COBO27 APRIL 2018 VOL 360 ISSUE 6387 355SCIENCE sciencemag.org27 APRIL 2018 VOLUME 360 ISSUE 6387CONTENTS376&409418Spatial entanglementNEWSIN BRIEF360 News at a glanceIN DEPTH 362 SEARCHING FOR A STONE AGE ODYSSEUSModern humans and even Neandertals may have plied the Mediterranean long ago By A.Lawler363 DATA TROVE HELPS PIN DOWN THE SHAPE OF THE MILKY WAYEuropes Gaia satellite reveals motions for 1.3 billion stars By D.Clery364 SIBERIAN SCULPTURE IS AMONG THE OLDEST MONUMENTAL ARTThe 11,600-year-old Shigir Idol offers an enigmatic glimpse of hunter-gatherers world view By A.Curry365 IS GENOME-GUIDED CANCER TREATMENT HYPED?New tailored therapies can work wonders,but the pace of development is slow By J.Kaiser366 ROBOTIC WEATHER BALLOON LAUNCHERS SPREAD IN ALASKAU.S.weather service union fears that automation threatens jobs and sacrifices forecasters local knowledge By J.Rosen367 CHRONICLING EMBRYOS,CELL BY CELL,GENE BY GENE Single-cell sequencing tracks cells gene activity during zebrafish and frog embryogenesis By E.Pennisi D.E.WAGNER ET AL.10.1126/science.aar4362;J.A.FARRELL ET AL.10.1126/science.aar3131;J.A.BRIGGS ET AL.10.1126/science.aar5780FEATURE 368 PEACE DIVIDENDColombian scientists race to study once-forbidden territory before it is lost to developmentor new conflict By L.Wade371 Cleaning up the killing fields By L.Wade381 NEXT-GENERATIONDIAGNOSTICS WITH CRISPRCRISPR-Cas biology promises rapid,accurate,and portable diagnostic tools By D.S.Chertow REPORTS PP.436,439,&444383 GNTER BLOBEL(19362018)Passionate cell biologist and inspirational mentor By P.Walter and D.AndersonPOLICY FORUM 384 ADVANCING THE ETHICS OF PALEOGENOMICSAncestral remains should be regarded not as“artifacts”but as human relatives who deserve respect By J.Bardill et al.BOOKS ET AL.386 THE AUTOMATED BATTLEFIELDA sober treatise on the future of warfare warns of the perils of autonomous robotic combatants By G.Lucas387 INCENTIVIZING RESPONSIBLE ANTIBIOTIC USEIn the fight against antimicrobial resistance,confronting economic challenges is key By R.LaxminarayanINSIGHTSPERSPECTIVES 374 REGENERATING TISSUESStudies of regeneration inform us about how to position organs By E.M.Tanaka RESEARCH ARTICLE P.404376 SPLIT,BUT STILL ATTACHEDEntanglement survives between spatially separated atoms of an atomic cloud after it expands By D.Cavalcanti REPORTS PP.409,413,&416377 DISRUPTING METABOLISM TOTREAT AUTOIMMUNITYDimethyl fumarate,a treatment for multiple sclerosis,inhibits Warburg metabolism By M.Matsushita and E.J.Pearce REPORT P.449378 WEIGHING ONE PROTEIN WITH LIGHTA light-scattering method allows rapid measurement of the mass of individual proteins By S.F.Lee and D.Klenerman REPORT P.423380 PLASTICS RECYCLING WITH A DIFFERENCEA novel plastic with useful properties can easily be recycled again and again By H.Sardon and A.P.Dove RESEARCH ARTICLE P.398368Rediscovering ColombiaDA_0427TOC.indd 3554/25/18 11:11 AMPublished by AAASon April 30,2018 http:/science.sciencemag.org/Downloaded from CREDITS:(FROM TOP)C.BICKEL/SCIENCE;KUTAY DENIZ ATABAY,SAMUEL A.LOCASIO,AND PETER W.REDDIEN27 APRIL 2018 VOL 360 ISSUE 6387 357SCIENCE sciencemag.orgCONTENTS27 APRIL 2018 VOLUME 360 ISSUE 6387RESEARCHIN BRIEF 393 From Science and other journalsRESEARCH ARTICLES 396 CILIA AND FLAGELLAAsymmetric distribution and spatial switching of dynein activity generates ciliary motility J.Lin and D.NicastroRESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aar1968397 BIOMECHANICSThe principles of cascading power limits in small,fast biological and engineered systems M.Ilton et al.RESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aao1082398 POLYMERSA synthetic polymer system with repeatable chemical recyclability J.-B.Zhu et al.PERSPECTIVE P.380404 REGENERATIONSelf-organization and progenitor targeting generate stable patterns in planarian regeneration K.D.Atabay et al.PERSPECTIVE P.374REPORTS QUANTUM ENTANGLEMENT409 Spatial entanglement patterns and Einstein-Podolsky-Rosen steering in Bose-Einstein condensates M.Fadel et al.413 Spatially distributed multipartite entanglement enables EPR steering of atomic clouds P.Kunkel et al.416 Entanglement between two spatially separated atomic modes K.Lange et al.PERSPECTIVE P.376419 ORGANIC CHEMISTRYCatalytic enantioselective Minisci-type addition to heteroarenes R.S.J.Proctor et al.423 BIOPHYSICSQuantitative mass imaging of single biological macromolecules G.Young et al.PERSPECTIVE P.378427 OCEAN HYPOXIALegacy nitrogen may prevent achievement of water quality goals in the Gulf of Mexico K.J.Van Meter et al.430 NEUROSCIENCEInterregional synaptic maps among engram cells underlie memory formation J.-H.Choi et al.ON THE COVERPortable diagnostic tools developed on the basis of CRISPR-Cas biology enable rapid,highly sensitive detection of pathogens in patient samples.A conceptual illustration of a Zika virus capsid drawn in the sand highlights the promise of deployin