5205AUGUST2016•VOL353ISSUE6299sciencemag.orgSCIENCE5AUGUST2016•VOLUME353•ISSUE6299CONTENTSPHOTO(TOPLEFT):©KENRICHARDSON556&557TheCRISPR-CasdefensesystemNEWSINBRIEF524NewsataglanceINDEPTH526VENEZUELA’SWOESHAMPERACCESSTOFOSSILTROVEOnlythemostdaringresearchersnowriskatriptopremiersiteintheAmericantropicsByL.Wade527ANTIAGINGTRIALUSINGYOUNGBLOODSTIRSCONCERNSCompanyplanstochargevolunteers$8000eachforplasmatransfusionsfromyoungdonorsByJ.Kaiser528NSFTRIESTWO-STEPREVIEW,DRAWINGPRAISE—ANDDARTSBriefpreliminaryproposalscan’tdojusticetoinnovativeresearch,scientistscomplainByJ.Mervis529ZIKAVACCINEHASAGOODSHOTModestimmuneresponsesoutwitvirusinmonkeystudies,buttrialswillbecomplexByJ.Cohen▶RESEARCHARTICLEBYP.ABBINKETAL.10.1126/science.aah6157530SYNCHROTRONAIMSTOBRIDGEDIVIDESINTHEMIDDLEEASTLightsourceinJordanisjustaboutreadytostartshiningByE.Stokstad531DISPUTEOVERPRESIDENT’SAGETEARSPASTEURINSTITUTEAPARTCenter’sboardofdirectorswassenthomeafterdenyingChristianBréchot,who’salmost65,asecondtermByT.RabesandratanaFEATURE532THESTORYTELLERWithRainerWeiss,gravitationalwavehunterandlikelyNobellaureate,there’sthestory—andthere’sthesubtextByA.Cho534ThelongroadtoLIGOByA.Cho543ANANOVIEWOFBATTERYOPERATIONSinglecathodeparticlesforlithium-ionbatteriesareanalyzedduringcyclingByS.B.Schougaard▶REPORTP.566POLICYFORUMS545THEFDAISPROHIBITEDFROMGOINGGERMLINEFullstop:U.S.CongressprecludeshumangermlinemodificationByI.G.CohenandE.Y.Adashi547CHINA-U.S.COOPERATIONTOADVANCENUCLEARPOWERMass-manufacturingandcoordinatedapprovalsarekeyByJ.Caoetal.BOOKSETAL.549ALMIGHTYByD.Zak,reviewedbyA.Wellerstein550TRUTHORTRUTHINESSByH.Wainer,reviewedbyC.J.PhillipsLETTERS551DECIPHERINGPVALUES:BEWAREFALSECERTAINTYByC.L.Hewittetal.551DECIPHERINGPVALUES:DEFININGSIGNIFICANCEByF.Phillips551EXPANDINGPROTECTEDAREASISNOTENOUGHByA.L.M.ChauvenetandM.Barnes552TECHNICALCOMMENTABSTRACTS552ERRATA532545INSIGHTSPERSPECTIVES538EMPERORYU’SGREATFLOODGeologicaldataprovidesupportforalegendaryfloodinChina~4000yearsagoByD.R.Montgomery...
