29JANUARY2016•VOL351ISSUE627242329JANUARY2016•VOLUME351•ISSUE6272CONTENTSPHOTO:(BOTTOMLEFT)LONNIEG.THOMPSON446SupergenesinbirdsNEWSINBRIEF428NewsataglanceINDEPTH430CANGERMANYENGINEERACOALEXIT?Debategrowsoverwhethernationcouldeliminateakeybutdirtyfuelby2040ByC.Schrader431RAREISOTOPESOFFERCLUESTOTHECHEMISTRYOFTHEPLANETNewlabtoolsbringexoticisotopicsignaturesintoviewByE.Hand433AFISHBACKFROMTHEDEADUnderstandinghowkillifishsurvivemonthswithoutoxygencouldhelpstrokevictimsByE.Pennisi434RESEARCHERSCLAIMTOFINDHIVSANCTUARIESThemostpowerfulantiretroviralsmaynotreachviruslurkinginsometissuesByJ.Cohen435CALCULUSPRECURSORUNCOVEREDINANCIENTBABYLONMathwhizzesleftprecociousgeometriccalculationsonclaytabletsby50B.C.E.ByR.Cowen▶REPORTP.482FEATURES436TIBET’SPRIMEVALICEThequestfortheworld’soldesticecouldyieldaRosettaStoneforhowAsiarespondstoachangingclimateByJ.Qiu440ACANCERLEGACYOnceviewedastragicanomalies,manychildhoodcancersmayhavetheirrootsininheritedmutationsByJ.Couzin-FrankelINSIGHTSBOOKSETAL.444CITYOFTHORNSByB.Rawlence,reviewedbyM.HyniePERSPECTIVES446AVIANSUPERGENESGeneticdatarevealhowtwocomplexbirdmatingsystemsevolvedByS.TaylorandL.Campagna448HOWECOSYSTEMSCHANGEConservationplanningmustaccommodatechangesinecosystemcompositiontoprotectbiodiversityByA.E.Magurran450HOWCANHIGHER-YIELDFARMINGHELPTOSPARENATURE?MechanismstolinkyieldincreaseswithconservationByB.Phalanetal.452PRESCRIPTIONDRUGSOBSCUREMICROBIOMEANALYSESPatientpopulationsshouldbestratifiedformedicationswhenlookingforgutmicrobialsignaturesofdiseaseByS.Devkota453TRACKINGTHEORIGINSOFTUMORIGENESISAzebrafishmodelallowsvisualizationofembryonicreprogrammingduringmelanomainitiationByS.BoumahdiandC.Blanpain▶RESEARCHARTICLEP.464LETTERS456ANECROGENOMICREGISTRY’SPOTENTIALByP.L.HedleyandM.Christiansen456TROPICALDAMS:TOBUILDORNOTTOBUILD?ByP.M.Fearnside457TECHNICALCOMMENTABSTRACTS457ONLINEBUZZ:TENURE’STENUREDEPARTMENTS427EDITORIALGlobalscienceengagementByGeraldineRichmond530WORKINGLIFEBattlingthebureaucracyhydraByJörgenJohansso...