Science 2018-01-05.pdf

4 5 JANUARY 2018 VOL 359 ISSUE 6371sciencemag.org SCIENCE5 JANUARY 2018 VOLUME 359 ISSUE 6371CONTENTS38Testing surface adhesionCREDITS:(CLOCKWISE FROM TOP)ROBERT W.CARPICK;KAVEH KAZEMI/GETTY IMAGES;ALMA(ESO/NAOJ/NRAO)/CC-BYNEWSIN BRIEF10 What to expect in 2018IN DEPTH 13 WATCHING THE TEEN BRAIN GROWOver a decade,researchers aim to follow 10,000 children through the challenges of adolescence By M.Wadman14 AMERICAS PEOPLED IN A SINGLE WAVE,ANCIENT GENOME REVEALSDNA from Alaskan infant suggests a long arctic sojourn By M.Price15 CANCER INSTITUTE HEAD TOUTS BIG DATA AND BASIC RESEARCHNCIs new director compares progress against cancer today to early strides against infectious disease By J.Kaiser16 MARS METHANE RISES AND FALLS WITH THE SEASONSScientists debate what could be causing annual cycles and occasional spikes By E.Hand17 GERMANY STEPS UP TO THE PLATE IN GLOBAL HEALTHA country long held back by its past emerges as a new leader,but its own research output is still lagging By K.Kupferschmidt18 EARTH-BASED PLANETFINDERS POWER UPIncreases in precision put Earth twins in reach By D.Clery INSIGHTSLETTERS 26 RESEARCH RESOLUTIONSPERSPECTIVES 29 THE GENOMICS OF CLIMATE CHANGEA study of yellow warblers identifies genomic regions involved in climate change adaptation By M.J.Fitzpatrick and A.H.Edelsparre REPORT P.8330 A NEW MITOTIC ACTIVITY COMES INTO FOCUSThe ATR kinase has a role in mitosis to promote chromosome segregation By J.C.Saldivar and K.A.Cimprich REPORT P.10832 PRECISION MEDICINE USING MICROBIOTAIntestinal microbiota influence cancer patient responses to immunotherapy By C.Jobin REPORTS PP.91,97,&104;PODCAST34 MIND THE SEAFLOORResearch and regulations must be integrated to protect seafloor biota from future mining impacts By A.Boetius and M.Haeckel36 LUNG INFLAMMATIONORIGINATING IN THE GUTParasite infection in the intestine can lead to inflammatory immune cells in the lung By J.Mjsberg and A.Rao REPORT P.11438 THE CONTACT SPORT OF ROUGH SURFACESApproximate models of interacting surfaces competed against a supercomputer solution By R.W.CarpickPOLICY FORUM 39 AIR POLLUTIONS HIDDEN IMPACTSExposure can affect labor productivity and human capital By J.Graff Zivin and M.NeidellBOOKS ET AL.41 THE ART OF SPACE-TIMEAn ambitious exhibition explores the intersection of the cosmos and contemporary artistry By E.Cartlidge42 SOCIAL SCIENCE,TODAYA breezy,personal guide provides a road map to solid computational social science research By D.LazerFEATURES 20 CHEMICAL MARTYRSThree decades after Iraqi forces unleashed mustard and nerve agents,scientists are unraveling the long-term effects By R.Stone23 HOW TO DEFEAT A NERVE AGENT By R.Stone24 WEAPONS IN WAITINGBy R.Stone VIDEO1020DA_0105TOC.indd 41/3/18 10:36 AMPublished by AAASon January 5,2018 http:/science.sciencemag.org/Downloaded from 5 JANUARY 2018 VOL 359 ISSUE 6371 5SCIENCE sciencemag.org72Mending underpressure36&114Innate lymphoid cell migration CREDITS:(CLOCKWISE FROM TOP LEFT)K.SUTLIFFE/SCIENCE;Y.YANAGISAWA ET AL;ISTOCK.COM/PAUL REEVES PHOTOGRAPHY DEPARTMENTS9 EDITORIAL Progress on reproducibilityBy Jeremy Berg126 WORKING LIFEThe harassment taxBy Lydia ZepedaRESEARCHIN BRIEF 43 From Science and other journalsREVIEW46 OCEANSDeclining oxygen in the global ocean and coastal waters D.Breitburg et al.REVIEW SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aam7240RESEARCH ARTICLES 47 CELL BIOLOGYPhase separation of a yeast prion protein promotes cellular fitness T.M.Franzmann et al.RESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aao565448 MALARIATransferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax J.Gruszczyk et al.55 COMPARATIVE GENOMICSRapid genome shrinkage in a self-fertile nematode reveals sperm competition proteins D.Yin et al.REPORTS 61 MATERIALS SCIENCEHydraulically amplified self-healing electrostatic actuators with muscle-like performance E.Acome et al.66 GAS GIANT PLANETSIn situ measurements of Saturns ionosphere show that it is dynamic and interacts with the rings J.-E.Wahlund et al.69 STELLAR ASTROPHYSICSAn excess of massive stars in the local 30 Doradus starburst F.R.N.Schneider et al.72 POLYMERSMechanically robust,readily repairable polymers via tailored noncovalent cross-linking Y.Yanagisawa et al.76 TOPOLOGICAL MATTERObservation of the quantum spin Hall effect up to 100 kelvin in a monolayer crystal S.Wu et al.80 CORAL REEFSSpatial and temporal patterns of mass bleaching of corals in the Anthropocene T.P.Hughes et al.83 ECOLOGICAL GENOMICSGenomic signals of selection predict climate-driven population declines in a migratory bird R.A.Bay et al.PERSPECTIVE P.2986 HIV SUSCEPTIBILITYElevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells V.Ramsuran et al.CANCER IMMUNOTHERAPY91 Gut microbiome influences efficacy of PD-1based immunotherapy against epithelial tumors B.Routy et al.97 Gut microbiome modulates response to antiPD-1 immunotherapy in melanoma patients V.Gopalakrishnan e