Science 2018-11-23.pdf

868 23 NOVEMBER 2018 VOL 362 ISSUE 6417sciencemag.org SCIENCE23 NOVEMBER 2018 VOLUME 362 ISSUE 6417CONTENTS886,889,&908Social basis of conservationCREDITS:(PHOTO)JOHN LEHMANN;(GRAPHIC)N.CARY/SCIENCENEWSIN BRIEF872 News at a glanceIN DEPTH 874 LUXE RESEARCH SHIP TO EXPLORE THE DEEP OCEANREV Ocean ramps up with$500 million from Norwegian fisheries and oil tycoon By E.Stokstad875 NASA TO PAY PRIVATE SPACE COMPANIES FOR MOON RIDESExperiments on commercial landers could confirm a wetter,more active moon By P.Voosen877 ARTIFICIAL CELLS GAIN COMMUNICATION SKILLSCell mimics make and pass on proteins that influence their neighbors By M.Leslie878 ASIA SET TO TAKE CENTER STAGE IN HIGGS STUDIESChina unveils full design for a$5 billion collider;Japan nears decision on its own plan By D.NormileINSIGHTSLETTERS 886 NEXTGEN VOICES:NURTURING CONNECTIONS TO THE ENVIRONMENT PERSPECTIVE P.889&REVIEW P.908PERSPECTIVES 889 HOW BEHAVIORAL SCIENCECAN HELP CONSERVATIONLeveraging cognitive biases and social influence can make conservation efforts more effective By J.Cinner LETTERS P.886&REVIEW P.908891 CELLULAR NETWORKS IN WOUND HEALINGMacrophage and fibroblast heterogeneity and plasticity control tissue fibrosis By S.Willenborg and S.A.Eming RESEARCH ARTICLE P.909892 THE DECLINE OF AFRICASLARGEST MAMMALSDid hominins play a role in the loss of megaherbivores?By R.Bobe and S.Carvalho REPORT P.938893 THE PARADOX OF MUTATIONS AND CANCEREsophageal tissue often contains driver mutations in people without cancer By S.J.Chanock REPORT P.911895 CHANGING CONCEPTS IN HEMATOPOIETIC STEM CELLSAnalyses of platelet and red blood cell lineages are redefining how we consider stemness By R.Yamamoto et al.897 THOMAS A.STEITZ(19402018)Biochemistry giant who illuminated ribosome structure By V.Ramakrishnan and R.Henderson880Fossil treasures from the Canadian Rockies879 GIANT MAMMAL COUSIN RIVALED EARLY DINOSAURSAncient plant eater grew as large as todays elephants By G.Vogel REPORT BY T.SULEJ ET AL.10.1126/SCIENCE.AAL4853FEATURE880 CRACKING THE CAMBRIANNew fossils and sites are helping make sense of the mysterious flowering of animal life half a billion years ago By J.Sokol PODCASTPublished by AAASon November 27,2018 http:/science.sciencemag.org/Downloaded from 23 NOVEMBER 2018 VOL 362 ISSUE 6417 869SCIENCE sciencemag.org922&926The versatile tungsten ditelluride952Molecular underpinnings of immunosuppressionDEPARTMENTS871 EDITORIAL Fixing the internet By Jonathan Zittrain966 WORKING LIFEFinding my inner Wonder WomanBy Camila H.CoelhoRESEARCHIN BRIEF 905 From Science and other journalsREVIEW908 AGRICULTUREIntensification for redesigned and sustainable agricultural systems J.PrettyREVIEW SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aav0294 LETTERS P.886&PERSPECTIVE P.889RESEARCH ARTICLES 909 SKIN REPAIRMyofibroblast proliferation and heterogeneity are supported by macrophages during skin repair B.A.Shook et al.RESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aar2971 PERSPECTIVE P.891910 DEVELOPMENTAL BIOLOGYMaternal Huluwa dictates the embryonic body axis through-catenin in vertebrates L.Yan et al.RESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aat1045911 GENETICSSomatic mutant clones colonize the human esophagus with age I.Martincorena et al.PERSPECTIVE P.893REPORTS 918 MASS SPECTROMETRYNeutral mass spectrometry of virus capsids above 100 megadaltons with nanomechanical resonators S.Dominguez-Medina et al.SUPERCONDUCTIVITY922 Gate-induced superconductivity in a monolayer topological insulator E.Sajadi et al.926 Electrically tunable low-density superconductivity in a monolayer topological insulator V.Fatemi et al.929 TOPOLOGICAL MATTERObservation of the topological Anderson insulator in disordered atomic wires E.J.Meier et al.933 METALLURGYMulticomponent intermetallic nanoparticles and superb mechanical behaviors of complex alloys T.Yang et al.938 PALEOECOLOGYPlio-Pleistocene decline of African megaherbivores:No evidence for ancient hominin impacts J.T.Faith et al.PERSPECTIVE P.892941 EPIDEMIOLOGYSocial network plasticity decreases disease transmission in a eusocial insect N.Stroeymeyt et al.945 NEUROSCIENCEEgocentric coding of external items in the lateral entorhinal cortex C.Wang et al.949 DEVELOPMENTAL BIOLOGYMolecular to organismal chirality is induced by the conserved myosin 1D G.Lebreton et al.952 IMMUNOLOGYStructural basis of latent TGF-1 presentation and activation by GARP on human regulatory T cells S.Linart et al.956 IMMUNOLOGYESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation S.Rhl et al.ON THE COVERA paleontologist in Canadas Kootenay National Park uses a rock saw to extract slabs bearing Cambrian fossils.In 1909,40 kilometers up this valley,paleontologists discovered the Burgess Shale,a 500-million-year-old formation that records animals soft features,such as eyes and guts.Today,paleontologists have shown that this type of preservation extends across many kilom