84426AUGUST2016•VOL353ISSUE6302sciencemag.orgSCIENCE26AUGUST2016•VOLUME353•ISSUE6302CONTENTS887AreceptorforretinolNEWSINBRIEF850NewsataglanceINDEPTH852ANTHROPOCENEPINNEDTOPOSTWARPERIODGeologistsvotetoseeka“goldenspike,”butpushforformalacceptancefacesskepticismByP.Voosen853NASAFLIESINTONAMIBIA’SCLOUDLABORATORYComminglingsmokeandfogposethornyclimatepuzzlesByE.Hand855CHOLESTEROLSCREENINGFORKIDSSPARKSDEBATE(AGAIN)Evidenceforuniversaltestingisinsufficient,taskforcesaysByJ.Couzin-Frankel856RESEARCHWATCHDOG’SNEWLEADERFACESSTAFFREVOLTORIheadtriestochartfuturecourse,butstaffwarnof“tensionsandconflict”inletterstohersuperiorsByJ.KaiserINSIGHTSPERSPECTIVES864HASSLESVERSUSPRICESHowcansubsidizedhealthproductsbesttargetthosewhovaluethem?ByB.A.Olken▶RESEARCHARTICLEP.889857THEEXOPLANETNEXTDOOREarth-likeplanetfound4light-yearsawayaroundProximaCentauri,thecloseststarByD.CleryFEATURES858THECARBONACCOUNTANTRichardHeedepinsmuchoftheresponsibilityforclimatechangeonjust90companies.Otherssaythat’sacop-outByD.Starr862EUROPE’SNEWHEPATITISPROBLEMManygetinfectedwithhepatitisE,andafewgetverysick.Howcanthevirusbestopped?ByK.Kupferschmidt88866BUILDINGMOLECULARCOMPLEXITYFROMSCRATCHThePauson-Khandcycloadditionreactionbuildsthetetracycliccoreof(+)-ryanodolByX.Verdaguer▶REPORTP.912867DOYOUSPEAKLION?Tobeeffective,conservationdecisionsmustbetransparentandbasedondiverseviewsByW.M.Adams869“WEATHERBOMB”INDUCEDSEISMICSIGNALSSeismicwavesgeneratedbyintensestormscanrevealdetailsofEarth’sinteriorByP.GerstoftandP.D.Bromirski▶REPORTP.919870PROLINEHYDROXYLATIONLINKEDTOAKTACTIVATIONOxygen-sensingenzymesregulatetheAktkinaseByM.VoulgarelisandP.N.Tsichlis▶REPORTP.929872APATHTOWARDUNDERSTANDINGNEURODEGENERATIONAfocusoncellbiologymayaccelerateprogressindiseasepreventionandcuresByK.S.Kosiketal.POLICYFORUM874ACHIEVINGGLOBALTARGETSFORANTIMICROBIALRESISTANCETheUNshouldpromotetargets,funding,andgovernanceByR.Laxminarayanetal.BOOKSETAL.876THEFUTUREOFTHREE-DIMENSIONALTHINKINGAnewholographicplatformholdspro...
